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Samples of 70% dark chocolate prepared for study with the USANS instrument at the Spallation Neutron Source. (Credit: ORNL/Genevieve Martin)

Tempering, the heating process that gives chocolate its appealing sheen and creamy texture, is a crucial part of crafting quality chocolate. But, at the molecular level, it gets a little tricky, and when done incorrectly, can render entire batches of chocolate gritty and unappetizing.

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

ORNL cybersecurity researchers Jared Smith (left) and Elliot Greenlee (right) participate in a demonstration day event to showcase how Akatosh, a new security analysis tool, quickly sorts through data to identify potential threats.

As technology continues to evolve, cybersecurity threats do as well. To better safeguard digital information, a team of researchers at the US Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) has developed Akatosh, a security analysis tool that works in conjunctio...

Ryan Kerekes is leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory. Photos by Genevieve Martin, ORNL.

As leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory, Kerekes heads an accelerated lab-directed research program to build virtual models of critical infrastructure systems like the power grid that can be used to develop ways to detect and repel cyber-intrusion and to make the network resilient when disruption occurs.

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

A conceptual illustration of proton-proton fusion in which two protons fuse to form a deuteron. Image courtesy of William Detmold.

Nuclear physicists are using the nation’s most powerful supercomputer, Titan, at the Oak Ridge Leadership Computing Facility to study particle interactions important to energy production in the Sun and stars and to propel the search for new physics discoveries Direct calculatio...

The interior of the Massachusetts Institute of Technology’s (MIT’s) Alcator C-Mod tokamak. A team led by Princeton Plasma Physics Laboratory’s C.S. Chang recently used the Titan supercomputer

The same fusion reactions that power the sun also occur inside a tokamak, a device that uses magnetic fields to confine and control plasmas of 100-plus million degrees. Under extreme temperatures and pressure, hydrogen atoms can fuse together, creating new helium atoms and simulta...

Ctherm on Biomass CSLM

With the licensing to Enchi Corporation of a microbe custom-designed to produce ethanol efficiently, Oak Ridge National Laboratory (ORNL) and the BioEnergy Science Center (BESC) mark the culmination of 10 years’ research into ways to improve biofuels production. Enchi ha...