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Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

Members of the international team simulated changes to the start times of monsoon seasons across the globe, with warm colors representing onset delays. Credit: Moetasim Ashfaq and Adam Malin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Scientists from the Department of Energy’s Oak Ridge National Laboratory and a dozen other international research institutions have produced the most elaborate set of projections to date that illustrates possible futures for major monsoon regions.

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

ORNL’s Bianca Haberl and Amy Elliott hold 3D-printed collimators — an invention that has been licensed to ExOne, a leading binder jet 3D printer company. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory has licensed a novel method to 3D print components used in neutron instruments for scientific research to the ExOne Company, a leading maker of binder jet 3D printing technology.

Simulations forecast nationwide increase in human exposure to extreme climate events

OAK RIDGE, Tenn., May 5, 2020 — By 2050, the United States will likely be exposed to a larger number of extreme climate events, including more frequent heat waves, longer droughts and more intense floods, which can lead to greater risks for human health, ecosystem stability and regional economies.

Ecosystem Ecologist Verity Salmon captures and analyzes field data from sites in in Alaska and Minnesota to inform earth system models that are being used to predict environmental change.

While some of her earth system modeling colleagues at ORNL face challenges such as processor allocation or debugging code, Verity Salmon prepares for mosquito swarms and the possibility of grizzly bears.

Data scientists at Oak Ridge National Laboratory have completed a study of long-term trends in the relationship between the timing of tree leafing and rising temperatures in the United States. The information is being incorporated into DOE’s Energy Exascale Earth System Model. Photo Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

A team of scientists led by Oak Ridge National Laboratory found that while all regions of the country can expect an earlier start to the growing season as temperatures rise, the trend is likely to become more variable year-over-year in hotter regions.

Arjun Shankar

The field of “Big Data” has exploded in the blink of an eye, growing exponentially into almost every branch of science in just a few decades. Sectors such as energy, manufacturing, healthcare and many others depend on scalable data processing and analysis for continued in...

ORNL Image

Researchers used neutrons to probe a running engine at ORNL’s Spallation Neutron Source

Methanotroph_OB3b_cells

A team led by the Department of Energy’s Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and sup...