3D-Printed Carbon Nanoelectrodes for In Vivo Neurotransmitter Sensing
Carbon nanoelectrodes were successfully fabricated by direct laser writing, enabling neurotransmitter detection in tiny biological organisms or synapses.
Significance and Impact
The 3D printing strategy allows for the design of customizable free-standing carbon electrodes with nanotips (nanoelectrode sensors).
– Freestanding carbon nanoelectrodes were fabricated by direct laser writing.
– 3D printed nanoelectrodes were insulated by thin layer of alumina and then polished to disk-shape by focused ion beam.
– Dopamine release in a tiny fruit fly brain was detected by the nanoelectrode.
Q. Cao, M. Shin, N. V. Lavrik, and B. J. Venton, "3-D Printed Carbon Nanoelectrodes for In Vivo Neurotransmitter Sensing," Nano Lett. 20, 6831-6836 (2020). DOI: 10.1021/acs.nanolett.0c02844