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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

ORNL Director Thomas Zacharia (center, seated) visited Robertsville Middle School to present a check in support of the school’s CubeSat efforts.

Last November a team of students and educators from Robertsville Middle School in Oak Ridge and scientists from Oak Ridge National Laboratory submitted a proposal to NASA for their Cube Satellite Launch Initiative in hopes of sending a student-designed nanosatellite named RamSat into...

A conceptual illustration of proton-proton fusion in which two protons fuse to form a deuteron. Image courtesy of William Detmold.

Nuclear physicists are using the nation’s most powerful supercomputer, Titan, at the Oak Ridge Leadership Computing Facility to study particle interactions important to energy production in the Sun and stars and to propel the search for new physics discoveries Direct calculatio...

The interior of the Massachusetts Institute of Technology’s (MIT’s) Alcator C-Mod tokamak. A team led by Princeton Plasma Physics Laboratory’s C.S. Chang recently used the Titan supercomputer

The same fusion reactions that power the sun also occur inside a tokamak, a device that uses magnetic fields to confine and control plasmas of 100-plus million degrees. Under extreme temperatures and pressure, hydrogen atoms can fuse together, creating new helium atoms and simulta...

Ctherm on Biomass CSLM

With the licensing to Enchi Corporation of a microbe custom-designed to produce ethanol efficiently, Oak Ridge National Laboratory (ORNL) and the BioEnergy Science Center (BESC) mark the culmination of 10 years’ research into ways to improve biofuels production. Enchi ha...

ORNL bioscience researcher Jerry Tuskan had an early interest in plant genetics.

It’s been 10 years since the Department of Energy first established a BioEnergy Science Center (BESC) at Oak Ridge National Laboratory, and researcher Gerald “Jerry” Tuskan has used that time and the lab’s and center’s resources and tools to make good on his college dreams of usi...

Pellet selector

When it’s up and running, the ITER fusion reactor will be very big and very hot, with more than 800 cubic meters of hydrogen plasma reaching 170 million degrees centigrade. The systems that fuel and control it, on the other hand, will be small and very cold. Pellets of frozen gas will be shot int...

Processing plutonium-238

Since its 1977 launch, NASA’s Voyager 1 spacecraft has travelled farther than any other piece of human technology. It is also the only human-made object to have entered interstellar space. More recently, the agency’s New Horizons mission flew past Pluto on July 14, giving us our first close-up lo...