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The Sycamore quantum processor. Credit: Erik Lucero/Google

A joint research team from Google Inc., NASA Ames Research Center, and the Department of Energy’s Oak Ridge National Laboratory has demonstrated that a quantum computer can outperform a classical computer 

Pictured in this early conceptual drawing, the Translational Research Capability planned for Oak Ridge National Laboratory will follow the design of research facilities constructed during the laboratory’s modernization campaign.

OAK RIDGE, Tenn., May 7, 2019—Energy Secretary Rick Perry, Congressman Chuck Fleischmann and lab officials today broke ground on a multipurpose research facility that will provide state-of-the-art laboratory space 

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.

Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.

As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

The EPB Control Center monitors the company’s assets such as substations and buildings.

OAK RIDGE, Tenn., Feb. 12, 2019—A team of researchers from the Department of Energy’s Oak Ridge and Los Alamos National Laboratories has partnered with EPB, a Chattanooga utility and telecommunications company, to demonstrate the effectiveness of metro-scale quantum key distribution (QKD).

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

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Researchers used neutron scattering at Oak Ridge National Laboratory’s Spallation Neutron Source to investigate bizarre magnetic behavior, believed to be a possible quantum spin liquid rarely found in a three-dimensional material. QSLs are exotic states of matter where magnetism continues to fluctuate at low temperatures instead of “freezing” into aligned north and south poles as with traditional magnets.

Joseph Lukens, Raphael Pooser, and Nick Peters (from left) of ORNL’s Quantum Information Science Group developed and tested a new interferometer made from highly nonlinear fiber in pursuit of improved sensitivity at the quantum scale. Credit: Carlos Jones

By analyzing a pattern formed by the intersection of two beams of light, researchers can capture elusive details regarding the behavior of mysterious phenomena such as gravitational waves. Creating and precisely measuring these interference patterns would not be possible without instruments called interferometers.