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ORNL staff members (from left) Ashley Shields, Michael Galloway, Ketan Maheshwari and Andrew Miskowiec are collaborating on a project focused on predicting and analyzing crystal structures of new uranium oxide phases. Credit: Jason Richards/ORNL

Scientists at the Department of Energy’s Oak Ridge National Laboratory are working to understand both the complex nature of uranium and the various oxide forms it can take during processing steps that might occur throughout the nuclear fuel cycle.

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Oak Ridge National Laboratory entrance sign

The unique process of accepting a new supercomputer is one of the most challenging projects a programmer may take on during a career. When the Oak Ridge Leadership Computing Facility’s (OLCF’s) Verónica Melesse Vergara came to the United States from Ecuador in 2005, she never would have dreamed of being part of such an endeavor. But just last fall, she was.

To develop complex materials with superior properties, Vera Bocharova uses diverse methods including broadband dielectric spectroscopy. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy; photographer Jason Richards

Vera Bocharova at the Department of Energy’s Oak Ridge National Laboratory investigates the structure and dynamics of soft materials—polymer nanocomposites, polymer electrolytes and biological macromolecules—to advance materials and technologies for energy, medicine and other applications.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Default image of ORNL entry sign

If you ask the staff and researchers at the Department of Energy’s Oak Ridge National Laboratory how they were first referred to the lab, you will get an extremely varied list of responses. Some may have come here as student interns, some grew up in the area and knew the lab by ...

SmartTruck, a small business in Greenville, SC, recently completed its first detailed unsteady analysis using modeling and simulation at the OLCF and became the first company to request certification from the EPA through CFD. Image Credit: SmartTruck

Long-haul tractor trailers, often referred to as “18-wheelers,” transport everything from household goods to supermarket foodstuffs across the United States every year. According to the Bureau of Transportation Statistics, these trucks moved more than 10 billion tons of goods—70.6 ...

ORNL cybersecurity researchers Jared Smith (left) and Elliot Greenlee (right) participate in a demonstration day event to showcase how Akatosh, a new security analysis tool, quickly sorts through data to identify potential threats.

As technology continues to evolve, cybersecurity threats do as well. To better safeguard digital information, a team of researchers at the US Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) has developed Akatosh, a security analysis tool that works in conjunctio...

Sergei Kalinin, director of the Institute for Functional Imaging of Materials at Oak Ridge National Laboratory, convenes experts in microscopy and computing to gain scientific insights that will inform design of advanced materials for energy and informati

Sergei Kalinin of the Department of Energy’s Oak Ridge National Laboratory knows that seeing something is not the same as understanding it. As director of ORNL’s Institute for Functional Imaging of Materials, he convenes experts in microscopy and computing to gain scientific insigh...

Schematic drawing of the boron nitride cell. Credit: University of Illinois at Chicago.

A new microscopy technique developed at the University of Illinois at Chicago allows researchers to visualize liquids at the nanoscale level — about 10 times more resolution than with traditional transmission electron microscopy — for the first time. By trapping minute amounts of...