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A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

Edmon Begoli

Artificial intelligence (AI) techniques have the potential to support medical decision-making, from diagnosing diseases to prescribing treatments. But to prioritize patient safety, researchers and practitioners must first ensure such methods are accurate.

International Conference on Neuromorphic Systems (ICONS)

Materials scientists, electrical engineers, computer scientists, and other members of the neuromorphic computing community from industry, academia, and government agencies gathered in downtown Knoxville July 23–25 to talk about what comes next in

Stephanie Galanie

Early career scientist Stephanie Galanie has applied her expertise in synthetic biology to a number of challenges in academia and private industry. She’s now bringing her skills in high-throughput bio- and analytical chemistry to accelerate research on feedstock crops as a Liane B. Russell Fellow at Oak Ridge National Laboratory.

Samples of 70% dark chocolate prepared for study with the USANS instrument at the Spallation Neutron Source. (Credit: ORNL/Genevieve Martin)

Tempering, the heating process that gives chocolate its appealing sheen and creamy texture, is a crucial part of crafting quality chocolate. But, at the molecular level, it gets a little tricky, and when done incorrectly, can render entire batches of chocolate gritty and unappetizing.

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

The interior of the Massachusetts Institute of Technology’s (MIT’s) Alcator C-Mod tokamak. A team led by Princeton Plasma Physics Laboratory’s C.S. Chang recently used the Titan supercomputer

The same fusion reactions that power the sun also occur inside a tokamak, a device that uses magnetic fields to confine and control plasmas of 100-plus million degrees. Under extreme temperatures and pressure, hydrogen atoms can fuse together, creating new helium atoms and simulta...

Ctherm on Biomass CSLM

With the licensing to Enchi Corporation of a microbe custom-designed to produce ethanol efficiently, Oak Ridge National Laboratory (ORNL) and the BioEnergy Science Center (BESC) mark the culmination of 10 years’ research into ways to improve biofuels production. Enchi ha...

ORNL’s Xiahan Sang unambiguously resolved the atomic structure of MXene, a 2D material promising for energy storage, catalysis and electronic conductivity. Image credit: Oak Ridge National Laboratory, U.S. Dept. of Energy; photographer Carlos Jones

Researchers have long sought electrically conductive materials for economical energy-storage devices. Two-dimensional (2D) ceramics called MXenes are contenders. Unlike most 2D ceramics, MXenes have inherently good conductivity because they are molecular sheets made from the carbides ...