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![Illustration of a nitrogen dioxide molecule (depicted in blue and purple) captured in a nano-size pore of an MFM-520 metal-organic framework material as observed using neutron vibrational spectroscopy at Oak Ridge National Laboratory. Image credit: ORNL/Jill Hemman](/sites/default/files/styles/list_page_thumbnail/public/2019-11/19-G00550_MOF_PR.png?h=e4fbc3eb&itok=3cY5NUpo)
An international team of scientists, led by the University of Manchester, has developed a metal-organic framework, or MOF, material
![CellSight allows for rapid mass spectrometry of individual cells. Credit: John Cahill, Oak Ridge National Laboratory/U.S. Dept of Energy](/sites/default/files/styles/list_page_thumbnail/public/2019-10/4CellSightPhoto_0.png?h=67debf3e&itok=fmsxiN_b)
Researchers at the Department of Energy’s Oak Ridge National Laboratory have received five 2019 R&D 100 Awards, increasing the lab’s total to 221 since the award’s inception in 1963.
![The configurational ensemble (a collection of 3D structures) of an intrinsically disordered protein, the N-terminal of c-Src kinase, which is a major signaling protein in humans. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2019-10/Petridis-PNAS-9.19.19-full%5B3%5D.png?h=d2706590&itok=7rUw2wkM)
Using the Titan supercomputer and the Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory, scientists have created the most accurate 3D model yet of an intrinsically disordered protein, revealing the ensemble of its atomic-level structures.
![Researchers explore the surface chemistry of a copper-chromium-iron oxide catalyst used to generate and purify hydrogen for industrial applications. Credit: Michelle Lehman and Adam Malin/Oak Ridge National Laboratory; U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2019-07/h2_graphic_v4_16x9.jpg?h=d1cb525d&itok=UXqJIEOH)
Collaborators at the Department of Energy’s Oak Ridge National Laboratory and U.S. universities used neutron scattering and other advanced characterization techniques to study how a prominent catalyst enables the “water-gas shift” reaction to purify and generate hydrogen at industrial scale.
![Snowflakes indicate phases of super-cold ice](/sites/default/files/styles/list_page_thumbnail/public/2019-05/19-G00404_Tulk_PR_0.jpg?h=e4fbc3eb&itok=5fn8aUhP)
An ORNL-led team's observation of certain crystalline ice phases challenges accepted theories about super-cooled water and non-crystalline ice. Their findings, reported in the journal Nature, will also lead to better understanding of ice and its various phases found on other planets, moons and elsewhere in space.
![Oak Ridge National Laboratory develops liquid helium auto-fill technology](/sites/default/files/styles/list_page_thumbnail/public/2019-05/2019-P02006.jpg?h=1116cd87&itok=D5pb2RTG)
OAK RIDGE, Tenn., May 14, 2019—Advanced Research Systems, Inc., has licensed a technology designed to automatically refill liquid helium used in laboratory equipment for low-temperature scientific experiments, which will reduce downtime, recover more helium and increase overall efficiency.
![Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2019-03/19-G00204_MR_graphic_Kovalevsky_proof5_2.png?h=b7fbb1a9&itok=wrZFNX-o)
OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.
![mirrorAsymmetry-NPDGamma_ORNL.jpg mirrorAsymmetry-NPDGamma_ORNL.jpg](/sites/default/files/styles/list_page_thumbnail/public/mirrorAsymmetry-NPDGamma_ORNL.jpg?itok=POtcSu48)
A team of scientists has for the first time measured the elusive weak interaction between protons and neutrons in the nucleus of an atom. They had chosen the simplest nucleus consisting of one neutron and one proton for the study.
![Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing. Using as much as 50 percent lignin by weight, a new composite material created at ORNL is well suited for use in 3D printing.](/sites/default/files/styles/list_page_thumbnail/public/2018-P09551.jpg?itok=q7Ri01Qb)
Scientists at the Department of Energy’s Oak Ridge National Laboratory have created a recipe for a renewable 3D printing feedstock that could spur a profitable new use for an intractable biorefinery byproduct: lignin.
![OAK RIDGE, Tenn., Nov. 27, 2018—The Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory has broken a new record by ending its first neutron production cycle in fiscal year 2019 at its design power level of 1.4 megawatts. OAK RIDGE, Tenn., Nov. 27, 2018—The Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory has broken a new record by ending its first neutron production cycle in fiscal year 2019 at its design power level of 1.4 megawatts.](/sites/default/files/styles/list_page_thumbnail/public/news/images/2015-P05970%5B7%5D.jpg?itok=MK35c7c-)
The Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory has broken a new record by ending its first neutron production cycle in fiscal year 2019 at its design power level of 1.4 megawatts.