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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

ORNL’s Fernanda Santos examines a soil sample at an NGEE Arctic field site in the Alaskan tundra in June 2022. Credit: Amy Breen, University of Alaska Fairbanks.

Wildfires are an ancient force shaping the environment, but they have grown in frequency, range and intensity in response to a changing climate. At ORNL, scientists are working on several fronts to better understand and predict these events and what they mean for the carbon cycle and biodiversity.

ORNL’s Shih-Chieh Kao has been named a 2023 fellow of the American Society of Civil Engineers’ Environmental & Water Resources Institute. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Shih-Chieh Kao, manager of the Water Power program at ORNL, has been named a fellow of the American Society of Civil Engineer’s Environmental & Water Resources Institute, or EWRI.

An illustration of the long-term evolution likely to occur as rising temperatures and subsequent thawing of frozen Arctic soils affects the northern Alaska tundra, as predicted by a high-performance model created by Oak Ridge National Laboratory. Credit: Adam Malin and Ethan Coon, ORNL/U.S. Dept. of Energy

Oak Ridge National Laboratory scientists set out to address one of the biggest uncertainties about how carbon-rich permafrost will respond to gradual sinking of the land surface as temperatures rise.

Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.

Seven scientists at the Department of Energy’s Oak Ridge National Laboratory have been named Battelle Distinguished Inventors, in recognition of their obtaining 14 or more patents during their careers at the lab. Credit: ORNL, U.S. Dept. of Energy

Seven scientists at the Department of Energy’s Oak Ridge National Laboratory have been named Battelle Distinguished Inventors, in recognition of their obtaining 14 or more patents during their careers at the lab.

Solar panels funded by the Honnold Foundation are installed in Adjuntas, Puerto Rico. Credit: Fabio Andrade

When Hurricane Maria battered Puerto Rico in 2017, winds snapped trees and destroyed homes, while heavy rains transformed streets into rivers. But after the storm passed, the human toll continued to grow as residents struggled without electricity for months. Five years later, power outages remain long and frequent.

The Department of Energy’s Office of Science has selected five Oak Ridge National Laboratory scientists for Early Career Research Program awards.

The Department of Energy’s Office of Science has selected five Oak Ridge National Laboratory scientists for Early Career Research Program awards.

Distinguished Inventors

Six scientists at the Department of Energy’s Oak Ridge National Laboratory were named Battelle Distinguished Inventors, in recognition of obtaining 14 or more patents during their careers at the lab.

Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body’s response to SARS-CoV-2. Credit: Jason B. Smith/ORNL, U.S. Dept. of Energy

A team led by Dan Jacobson of Oak Ridge National Laboratory used the Summit supercomputer at ORNL to analyze genes from cells in the lung fluid of nine COVID-19 patients compared with 40 control patients.