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Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

Scientists at ORNL have created a rhizosphere-on-a-chip research platform, a miniaturized environment to study the ecosystem around poplar tree roots for insights into plant health and soil carbon sequestration. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists at ORNL have created a miniaturized environment to study the ecosystem around poplar tree roots for insights into plant health and soil carbon sequestration.

Samarthya Bhagia examines a sample of a thermoplastic composite material additively manufactured using poplar wood and polylactic acid. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Chemical and environmental engineer Samarthya Bhagia is focused on achieving carbon neutrality and a circular economy by designing new plant-based materials for a range of applications from energy storage devices and sensors to environmentally friendly bioplastics.

Melanie Mayes is an ORNL biogeochemist studying soil carbon cycling across varied ecosystems, including in urban environments. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Science has taken Melanie Mayes from Tennessee to the tropics, studying some of the most important ecosystems in the world.

ORNL researchers deploy a gas trap to measure ebullitive (bubbling) emissions of methane at the Melton Dam in East Tennessee. The trap is deployed for ~ 24 hours to allow gas to accumulate in the trap. Credit: Carlos Jones/ORNL, US Dept. of Energy

As the United States moves toward more sustainable and renewable sources of energy, hydropower is expected to play a pivotal role in integrating more intermittent renewables like wind and solar to the electricity grid

Microorganisms may provide hope that peatlands can withstand hotter temperatures in a changing climate.

Microorganisms may provide hope that peatlands can withstand hotter temperatures in a changing climate.

Scattering-type scanning near-field optical microscopy, a nondestructive technique in which the tip of the probe of a microscope scatters pulses of light to generate a picture of a sample, allowed the team to obtain insights into the composition of plant cell walls. Credit: Ali Passian/ORNL, U.S. Dept. of Energy

To optimize biomaterials for reliable, cost-effective paper production, building construction, and biofuel development, researchers often study the structure of plant cells using techniques such as freezing plant samples or placing them in a vacuum.

ORNL scientists created a geodemographic cluster for the Atlanta metro area that identifies risk factors related to climate impacts. Credit: ORNL/U.S. Dept. of Energy

A new capability to identify urban neighborhoods, down to the block and building level, that are most vulnerable to climate change could help ensure that mitigation and resilience programs reach the people who need them the most.

Jennifer Morrell-Falvey leads the Molecular and Cellular Imaging group at ORNL, advancing new insights in several scientific areas, including the interactions between plants and microbes that influence ecosystem health and carbon cycling. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Jennifer Morrell-Falvey’s interest in visualizing the science behind natural processes was what drew her to ORNL in what she expected to be a short stint some 18 years ago. 

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Tackling the climate crisis and achieving an equitable clean energy future are among the biggest challenges of our time.