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From left to right, Cortney Piper, executive director of the Tennessee Advanced Energy Business Council; Susan Hubbard, ORNL deputy for science and technology; Dan Miller, innovation Crossroads program lead; and Mike Paulus, ORNL director of technology transfer, attend the Innovation Crossroads Showcase at the Knoxville Chamber on Sept. 22. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A crowd of investors and supporters turned out for last week’s Innovation Crossroads Showcase at the Knoxville Chamber as part of Innov865 Week. Sponsored by ORNL and the Tennessee Advanced Energy Business Council, the event celebrated deep-tech entrepreneurs and the Oak Ridge Corridor as a growing energy innovation hub for the nation.

ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.

ORNL used novel additive manufacturing techniques to 3D print channel fasteners for Framatome’s boiling water reactor fuel assembly. Four components, like the one shown here, were installed at the TVA Browns Ferry nuclear plant. Credit: Framatome

Four first-of-a-kind 3D-printed fuel assembly brackets, produced at the Department of Energy’s Manufacturing Demonstration Facility at Oak Ridge National Laboratory, have been installed and are now under routine operating

ORNL researchers in advanced manufacturing, materials science and engineering collaborated to produce face shields and reusable mask molds so that industry can quickly mass produce. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

The University of Texas at San Antonio (UTSA) has formally launched the Cybersecurity Manufacturing Innovation Institute (CyManII), a $111 million public-private partnership.

These fuel assembly brackets, manufactured by ORNL in partnership with Framatome and Tennessee Valley Authority, are the first 3D-printed safety-related components to be inserted into a nuclear power plant. Credit: Fred List/ORNL, U.S. Dept. of Energy

The Transformational Challenge Reactor, or TCR, a microreactor built using 3D printing and other new advanced technologies, could be operational by 2024.

The CrossVis application includes a parallel coordinates plot (left), a tiled image view (right) and other interactive data views. Credit: Chad Steed/Oak Ridge National Laboratory, U.S. Dept. of Energy

From materials science and earth system modeling to quantum information science and cybersecurity, experts in many fields run simulations and conduct experiments to collect the abundance of data necessary for scientific progress.

Coronavirus graphic

In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.

Researchers discovered the Tennessee cavesnail, Antrorbis tennesseensis, in caves near Oak Ridge National Laboratory. The snail measures in at less than 2 millimeters long. Credit: Nathaniel Shoobs and Matthew Niemiller

Sometimes conducting big science means discovering a species not much larger than a grain of sand.

Costas Tsouris portrait

While Tsouris’ water research is diverse in scope, its fundamentals are based on basic science principles that remain largely unchanged, particularly in a mature field like chemical engineering.