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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

The electromagnetic isotope separator system operates by vaporizing an element such as ruthenium into the gas phase, converting the molecules into an ion beam, and then channeling the beam through magnets to separate out the different isotopes.

A tiny vial of gray powder produced at the Department of Energy’s Oak Ridge National Laboratory is the backbone of a new experiment to study the intense magnetic fields created in nuclear collisions.

Kevin Robb, a staff scientist at the Department of Energy’s Oak Ridge National Laboratory, is taking what he learned from developing the Liquid Salt Test Loop—a key tool in deploying molten salt technology applications

Thanks in large part to developing and operating a facility for testing molten salt reactor (MSR) technologies, nuclear experts at the Energy Department’s Oak Ridge National Laboratory (ORNL) are now tackling the next generation of another type of clean energy—concentrating ...

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

ORNL Image

For the past six years, some 140 scientists from five institutions have traveled to the Arctic Circle and beyond to gather field data as part of the Department of Energy-sponsored NGEE Arctic project. This article gives insight into how scientists gather the measurements that inform t...

ORNL Director Thomas Zacharia (center, seated) visited Robertsville Middle School to present a check in support of the school’s CubeSat efforts.

Last November a team of students and educators from Robertsville Middle School in Oak Ridge and scientists from Oak Ridge National Laboratory submitted a proposal to NASA for their Cube Satellite Launch Initiative in hopes of sending a student-designed nanosatellite named RamSat into...

Germina Ilas (left) and Ian Gauld review spent fuel data entries in the SFCOMPO 2.0 database.
Oak Ridge National Laboratory provided significant contributions and coordination in the development of the Nuclear Energy Agency’s (NEA’s) recently released Spent Fuel Isotopic Composition (SFCOMPO) 2.0—the world’s largest open database for spent
Processing plutonium-238

Since its 1977 launch, NASA’s Voyager 1 spacecraft has travelled farther than any other piece of human technology. It is also the only human-made object to have entered interstellar space. More recently, the agency’s New Horizons mission flew past Pluto on July 14, giving us our first close-up lo...