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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

SmartTruck, a small business in Greenville, SC, recently completed its first detailed unsteady analysis using modeling and simulation at the OLCF and became the first company to request certification from the EPA through CFD. Image Credit: SmartTruck

Long-haul tractor trailers, often referred to as “18-wheelers,” transport everything from household goods to supermarket foodstuffs across the United States every year. According to the Bureau of Transportation Statistics, these trucks moved more than 10 billion tons of goods—70.6 ...

The electromagnetic isotope separator system operates by vaporizing an element such as ruthenium into the gas phase, converting the molecules into an ion beam, and then channeling the beam through magnets to separate out the different isotopes.

A tiny vial of gray powder produced at the Department of Energy’s Oak Ridge National Laboratory is the backbone of a new experiment to study the intense magnetic fields created in nuclear collisions.

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

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For the past six years, some 140 scientists from five institutions have traveled to the Arctic Circle and beyond to gather field data as part of the Department of Energy-sponsored NGEE Arctic project. This article gives insight into how scientists gather the measurements that inform t...

ORNL researchers Todd Toops, Charles Finney, and Melanie DeBusk (left to right) hold an example of a particulate filter used to collect harmful emissions in vehicles.

Researchers are looking to neutrons for new ways to save fuel during the operation of filters that clean the soot, or carbon and ash-based particulate matter, emitted by vehicles. A team of researchers from the Energy and Transportation Science Division at the Department of En...

ORNL’s Xiahan Sang unambiguously resolved the atomic structure of MXene, a 2D material promising for energy storage, catalysis and electronic conductivity. Image credit: Oak Ridge National Laboratory, U.S. Dept. of Energy; photographer Carlos Jones

Researchers have long sought electrically conductive materials for economical energy-storage devices. Two-dimensional (2D) ceramics called MXenes are contenders. Unlike most 2D ceramics, MXenes have inherently good conductivity because they are molecular sheets made from the carbides ...

Advanced materials take flight in the LEAP engine, featuring ceramic matrix composites developed over a quarter-century by GE with help from DOE and ORNL. Image credit: General Electric

Ceramic matrix composite (CMC) materials are made of coated ceramic fibers surrounded by a ceramic matrix. They are tough, lightweight and capable of withstanding temperatures 300–400 degrees F hotter than metal alloys can endure. If certain components were made with CMCs instead o...