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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Modified deep-learning algorithms unveil features of shape-shifting proteins

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Alex Roschli in front of BAAM

Alex Roschli: Keeping additive manufacturing machines humming

Alex Roschli is no stranger to finding himself in unique situations. After all, the early career researcher in ORNL’s Manufacturing Systems Research group bears a last name that only 29 other people share in the United States, and he’s certain he’s the only Roschli (a moniker that hails from Switzerland) with the first name Alex.

The concrete parts are installed in a residential and commercial tower (above center and below) on the site of the Domino Sugar Factory along the waterfront in Brooklyn. Windows in the tower resemble sugar crystals. Image credit: Gate Precast

3D printing shapes building industry, creates rapid construction potential

A residential and commercial tower under development in Brooklyn that is changing the New York City skyline has its roots in research at the Department of Energy’s Oak Ridge National Laboratory.

ORNL will use state-of-the-art R&D tools at the Battery Manufacturing Facility to develop new methods for separating and reclaiming valuable materials from spent EV batteries.

ORNL supports new DOE lithium-ion battery recycling center

The use of lithium-ion batteries has surged in recent years, starting with electronics and expanding into many applications, including the growing electric and hybrid vehicle industry. But the technologies to optimize recycling of these batteries have not kept pace.

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Tree of life: Poplar studies yield human cancer insights

While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Rose Ruther and Jagjit Nanda have been collaborating to develop a membrane for a low-cost redox flow battery for grid-scale energy storage.

Novel membrane advances low-cost, grid-scale energy storage

Oak Ridge National Laboratory scientists have developed a crucial component for a new kind of low-cost stationary battery system utilizing common materials and designed for grid-scale electricity storage. Large, economical electricity storage systems can benefit the nation’s grid ...

The electromagnetic isotope separator system operates by vaporizing an element such as ruthenium into the gas phase, converting the molecules into an ion beam, and then channeling the beam through magnets to separate out the different isotopes.

ORNL produces rare ruthenium isotope for atom smashing experiment

A tiny vial of gray powder produced at the Department of Energy’s Oak Ridge National Laboratory is the backbone of a new experiment to study the intense magnetic fields created in nuclear collisions.

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

Made in the USA: Department of Energy labs help advance technology to ensure supply of key medical isotopes

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

ORNL Director Thomas Zacharia (center, seated) visited Robertsville Middle School to present a check in support of the school’s CubeSat efforts.

Prepared for lift-off

Last November a team of students and educators from Robertsville Middle School in Oak Ridge and scientists from Oak Ridge National Laboratory submitted a proposal to NASA for their Cube Satellite Launch Initiative in hopes of sending a student-designed nanosatellite named RamSat into...