Skip to main content
Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Neutron scattering allowed direct observation of how aurein induces lateral segregation in the bacteria membranes, which creates instability in the membrane structure. This instability causes the membranes to fail, making harmful bacteria less effective.

As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.

Coexpression_hi-res_image[1].jpg

While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Picture2.png

Oak Ridge National Laboratory scientists studying fuel cells as a potential alternative to internal combustion engines used sophisticated electron microscopy to investigate the benefits of replacing high-cost platinum with a lower cost, carbon-nitrogen-manganese-based catalyst.

2018-P07635 BL-6 user - Univ of Guelph-6004R_sm[2].jpg

A team of scientists, led by University of Guelph professor John Dutcher, are using neutrons at ORNL’s Spallation Neutron Source to unlock the secrets of natural nanoparticles that could be used to improve medicines.

Physics_silicon-detectors.jpg

Physicists turned to the “doubly magic” tin isotope Sn-132, colliding it with a target at Oak Ridge National Laboratory to assess its properties as it lost a neutron to become Sn-131.

Methanogen_mercury_study3.jpg

Biologists from Oak Ridge National Laboratory and the Smithsonian Environmental Research Center have confirmed that microorganisms called methanogens can transform mercury into the neurotoxin methylmercury with varying efficiency across species.

ORNL cybersecurity researchers Jared Smith (left) and Elliot Greenlee (right) participate in a demonstration day event to showcase how Akatosh, a new security analysis tool, quickly sorts through data to identify potential threats.

As technology continues to evolve, cybersecurity threats do as well. To better safeguard digital information, a team of researchers at the US Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) has developed Akatosh, a security analysis tool that works in conjunctio...

Researchers analyzed 15 years of data across 16 neighborhoods, shown in orange, in the Las Vegas Valley Water District to determine whether one home’s participation in the utility’s water conservation program had a measureable effect on their neighbors’ l

A team led by Oak Ridge National Laboratory has discovered that residents living in arid environments share a desire for water security, which can ultimately benefit entire neighborhoods. Las Vegas, Nevada’s water utility was the first utility in the United States to implement ...

Ryan Kerekes is leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory. Photos by Genevieve Martin, ORNL.

As leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory, Kerekes heads an accelerated lab-directed research program to build virtual models of critical infrastructure systems like the power grid that can be used to develop ways to detect and repel cyber-intrusion and to make the network resilient when disruption occurs.