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ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy

Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at ORNL. 

ORNL’s Larry York studies how plant root traits contribute to crop productivity. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Biologist Larry York’s fascination with plant roots has spurred his research across four continents and inspired him to create accessible tools that enable others to explore the underground world.

Merlin Theodore, advanced fibers manufacturing group leader and Tuskegee University alumna, will guide Oak Ridge National Laboratory’s collaboration with the university, through which students and researchers work together to advance the development of bioderived materials. Credit: ORNL, U.S. Dept. of Energy

ORNL and Tuskegee University have formed a partnership to develop new biodegradable materials for use in buildings, transportation and biomedical applications.

Planting native grasses such as the bioenergy crop switchgrass can restore habitat for birds like this Eastern kingbird. Credit: Chris Lituma/West Virginia University

An analysis by Oak Ridge National Laboratory shows that using less-profitable farmland to grow bioenergy crops such as switchgrass could fuel not only clean energy, but also gains in biodiversity.

In a study, ORNL researchers concluded that the most direct path to plastic upcycling is through designing polymers specifically for reuse, which would allow the material to be converted into high-value products. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers determined that designing polymers specifically with upcycling in mind could reduce future plastic waste considerably and facilitate a circular economy where the material is used repeatedly.

U.S. Secretary of Energy Granholm tours ORNL’s world-class science facilities

Energy Secretary Jennifer Granholm visited ORNL on Nov. 22 for a two-hour tour, meeting top scientists and engineers as they highlighted projects and world-leading capabilities that address some of the country’s most complex research and technical challenges. 

Ashleigh Kimberlin and Mikayla Molnar achieve success with a gas-trapping apparatus for Ac-225 production. Credit: ORNL, U.S. Dept. of Energy

In experiment after experiment, the synthetic radioisotope actinium-225 has shown promise for targeting and attacking certain types of cancer cells.

Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers. Credit: ORNL, U.S. Dept. of Energy

Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers, according to a bibliometric analysis conducted by the scientific publication analytics firm Clarivate.

Biopsy from the tubular esophagus showing incomplete intestinal metaplasia, goblet cells with interposed cells having gastric foveolar-type mucin consistent with Barrett esophagus. Negative for dysplasia. H&E stain. Credit: Creative Commons

A team including researchers from the Department of Energy’s Oak Ridge National Laboratory has developed a digital tool to better monitor a condition known as Barrett’s esophagus, which affects more than 3 million people in the United States.

Carrie Eckert

Carrie Eckert applies her skills as a synthetic biologist at ORNL to turn microorganisms into tiny factories that produce a variety of valuable fuels, chemicals and materials for the growing bioeconomy.