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The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

Hector J. Santos-Villalobos, left, and Oscar A. Martinez

Two staff members at the Department of Energy’s Oak Ridge National Laboratory have received prestigious HENAAC and Luminary Awards from Great Minds in STEM, a nonprofit organization that focuses on promoting STEM careers in underserved 

This photo shows the interior of the vessel of the General Atomics DIII-D National Fusion Facility in San Diego, where ORNL researchers are testing the suitability of tungsten to armor the inside of a fusion device. Credit: General Atomics

The inside of future nuclear fusion energy reactors will be among the harshest environments ever produced on Earth. What’s strong enough to protect the inside of a fusion reactor from plasma-produced heat fluxes akin to space shuttles reentering Earth’s atmosphere?

Enzyme activity during organophosphate poisoning

Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.

ORNL’s Drew Elliott served as a major collaborator in upgrading the Princeton Plasma Physics Laboratory’s Lithium Tokamak Experiment-Beta. Credit: Robert Kaita, Princeton Plasma Physics Laboratory

Lithium, the silvery metal that powers smart phones and helps treat bipolar disorders, could also play a significant role in the worldwide effort to harvest on Earth the safe, clean and virtually limitless fusion energy that powers the sun and stars.

An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists at ORNL used neutron scattering and supercomputing to better understand how an organic solvent and water work together to break down plant biomass, creating a pathway to significantly improve the production of renewable

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

From left, Peter Jiang, Elijah Martin and Benjamin Sulman have been selected for Early Career Research Program awards from the Department of Energy's Office of Science. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

The Department of Energy’s Office of Science has selected three Oak Ridge National Laboratory scientists for Early Career Research Program awards.

Juergen Rapp

Juergen Rapp, a distinguished R&D staff scientist in ORNL’s Fusion Energy Division in the Nuclear Science and Engineering Directorate, has been named a fellow of the American Nuclear Society

ORNL scientists are currently using Proto-MPEX to perform necessary research and development that is needed to build MPEX. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Temperatures hotter than the center of the sun. Magnetic fields hundreds of thousands of times stronger than the earth’s. Neutrons energetic enough to change the structure of a material entirely.