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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

Frontier supercomputer

Innovations in artificial intelligence are rapidly shaping our world, from virtual assistants and chatbots to self-driving cars and automated manufacturing.

Matt Sieger. Credit: Carlos Jones/ORNL

The Oak Ridge Leadership Computing Facility’s Matt Sieger has been named the project director for the OLCF-6 effort. This next OLCF undertaking will plan and build a world-class successor to the OLCF’s still-new exascale system, Frontier.

The Frontier supercomputer at ORNL remains in the number one spot on the May 2023 TOP500 rankings, with an updated high-performance Linpack score of 1.194 exaflops. Engineers at the Oak Ridge Leadership Computing Facility, which houses Frontier and its predecessor Summit, expect that Frontier’s speeds could ultimately top 1.4 exaflops, or 1.4 quintillion calculations per second. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

With the world’s first exascale supercomputing system now open to full user operations, research teams are harnessing Frontier’s power and speed to tackle some of the most challenging problems in modern science.

Michael Parks

ORNL has named Michael Parks director of the Computer Science and Mathematics Division within ORNL’s Computing and Computational Sciences Directorate. His hiring became effective March 13.

UKAEA will provide novel fusion materials to be irradiated in ORNL’s HFIR facility over the next four years. From left, Kathy McCarthy, Jeremy Busby, Mickey Wade, Prof Sir Ian Chapman (UKAEA CEO), Cynthia Jenks and Yutai Kato will represent this new partnership. Not pictured: Dr. Amanda Quadling, UKAEA’s Director of Materials Research Facility. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

ORNL has entered a strategic research partnership with the United Kingdom Atomic Energy Authority, or UKAEA, to investigate how different types of materials behave under the influence of high-energy neutron sources. The $4 million project is part of UKAEA's roadmap program, which aims to produce electricity from fusion.

Gina Tourassi, left, has been appointed as director of the National Center for Computational Sciences at Oak Ridge National Laboratory. Tourassi replaces NCCS director Jim Hack, who will transition to a strategic leadership role in CCSD. Credit: Carlos Jones/ORNL

Gina Tourassi has been appointed as director of the National Center for Computational Sciences, a division of the Computing and Computational Sciences Directorate at Oak Ridge National Laboratory.

U.S. Department of Energy and Cray to Deliver Record-Setting Frontier Supercomputer at ORNL

OAK RIDGE, Tenn., May 7, 2019—The U.S. Department of Energy today announced a contract with Cray Inc. to build the Frontier supercomputer at Oak Ridge National Laboratory, which is anticipated to debut in 2021 as the world’s most powerful computer with a performance of greater than 1.5 exaflops.

Pictured in this early conceptual drawing, the Translational Research Capability planned for Oak Ridge National Laboratory will follow the design of research facilities constructed during the laboratory’s modernization campaign.

OAK RIDGE, Tenn., May 7, 2019—Energy Secretary Rick Perry, Congressman Chuck Fleischmann and lab officials today broke ground on a multipurpose research facility that will provide state-of-the-art laboratory space 

Illustration of the intricate organization of the PKA structure, wherein different parts of the protein are connected through elaborate hydrogen bonding networks (dashed yellow lines), glued together by the hydrophobic assemblies (light blue and orange volumes)—all working together to build the functional active site. Insert shows protonation of the transferred phosphoryl group (cyan mesh) and its many interactions with water and the active site amino acid residues. Credit: Jill Hemman/ORNL

OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.