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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

Alex Roschli in front of BAAM

Alex Roschli is no stranger to finding himself in unique situations. After all, the early career researcher in ORNL’s Manufacturing Systems Research group bears a last name that only 29 other people share in the United States, and he’s certain he’s the only Roschli (a moniker that hails from Switzerland) with the first name Alex.

The concrete parts are installed in a residential and commercial tower (above center and below) on the site of the Domino Sugar Factory along the waterfront in Brooklyn. Windows in the tower resemble sugar crystals. Image credit: Gate Precast

A residential and commercial tower under development in Brooklyn that is changing the New York City skyline has its roots in research at the Department of Energy’s Oak Ridge National Laboratory.

Laminations such as these are compiled to form the core of modern electric vehicle motors. ORNL has developed a software toolkit to speed the development of new motor designs and to improve the accuracy of their real-world performance.

Oak Ridge National Laboratory scientists have created open source software that scales up analysis of motor designs to run on the fastest computers available, including those accessible to outside users at the Oak Ridge Leadership Computing Facility.

Researchers used machine learning methods on the ORNL Compute and Data Environment for Science, or CADES, to map vegetation communities in the Kougarok Watershed on the Seward Peninsula of Alaska. The colors denote different types of vegetation, such as w

A team of scientists led by Oak Ridge National Laboratory used machine learning methods to generate a high-resolution map of vegetation growing in the remote reaches of the Alaskan tundra.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

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Scientists at Oak Ridge National Laboratory and Hypres, a digital superconductor company, have tested a novel cryogenic, or low-temperature, memory cell circuit design that may boost memory storage while using less energy in future exascale and quantum computing applications.

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Oak Ridge National Laboratory scientists studying fuel cells as a potential alternative to internal combustion engines used sophisticated electron microscopy to investigate the benefits of replacing high-cost platinum with a lower cost, carbon-nitrogen-manganese-based catalyst.

SmartTruck, a small business in Greenville, SC, recently completed its first detailed unsteady analysis using modeling and simulation at the OLCF and became the first company to request certification from the EPA through CFD. Image Credit: SmartTruck

Long-haul tractor trailers, often referred to as “18-wheelers,” transport everything from household goods to supermarket foodstuffs across the United States every year. According to the Bureau of Transportation Statistics, these trucks moved more than 10 billion tons of goods—70.6 ...