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Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

Each point on the sphere of this visual representation of arbitrary frequency-bin qubit states corresponds to a unique quantum state, and the gray sections represent the measurement results. The zoomed-in view illustrates examples of three quantum states plotted next to their ideal targets (blue dots). Credit: Joseph Lukens/ORNL, U.S. Dept. of Energy

A team of researchers at Oak Ridge National Laboratory and Purdue University has taken an important step toward this goal by harnessing the frequency, or color, of light. Such capabilities could contribute to more practical and large-scale quantum networks exponentially more powerful and secure than the classical networks we have today.

Verónica Melesse Vergara speaks with third and fourth graders at East Side Intermediate School in Brownsville. Credit: ORNL, U.S. Dept. of Energy

Twenty-seven ORNL researchers Zoomed into 11 middle schools across Tennessee during the annual Engineers Week in February. East Tennessee schools throughout Oak Ridge and Roane, Sevier, Blount and Loudon counties participated, with three West Tennessee schools joining in.

SCGSR Awardee Jacob Zettlemoyer, Indiana University Bloomington, led data analysis and worked with ORNL’s Mike Febbraro on coatings, shown under blue light, to shift argon light to visible wavelengths to boost detection. Credit: Rex Tayloe/Indiana University

The COHERENT particle physics experiment at the Department of Energy’s Oak Ridge National Laboratory has firmly established the existence of a new kind of neutrino interaction.

Distinguished Inventors

Six scientists at the Department of Energy’s Oak Ridge National Laboratory were named Battelle Distinguished Inventors, in recognition of obtaining 14 or more patents during their careers at the lab.

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS. Credit: ORNL, U.S. Dept. of Energy

Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS.

The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

Oak Ridge National Laboratory entrance sign

Geoffrey L. Greene, a professor at the University of Tennessee, Knoxville, who holds a joint appointment with ORNL, will be awarded the 2021 Tom Bonner Prize for Nuclear Physics from the American Physical Society.

ORNL researchers and energy storage startup Sparkz have developed a cobalt-free cathode material for use in lithium-ion batteries Credit: Ilias Belharouak/Oak Ridge National Laboratory, U.S. Dept. of Energy

Four research teams from the Department of Energy’s Oak Ridge National Laboratory and their technologies have received 2020 R&D 100 Awards.