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Frontier supercomputer

A multi-institutional team, led by a group of investigators at Oak Ridge National Laboratory, has been studying various SARS-CoV-2 protein targets, including the virus’s main protease. The feat has earned the team a finalist nomination for the Association of Computing Machinery, or ACM, Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research.

An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.

Chuck Kessel

Chuck Kessel was still in high school when he saw a scientist hold up a tiny vial of water and say, “This could fuel a house for a whole year.”

Blue sky above ORNL campus.

ORNL and three partnering institutions have received $4.2 million over three years to apply artificial intelligence to the advancement of complex systems in which human decision making could be enhanced via technology.

New virtual tours of ORNL facilities include the Building Technologies Research and Integration Center, shown in dollhouse view. Credit: ORNL, U.S. Dept. of Energy

ORNL has added 10 virtual tours to its campus map, each with multiple views to show floor plans, rotating dollhouse views and 360-degree navigation. As a user travels through a map, pop-out informational windows deliver facts, videos, graphics and links to other related content.

Data collection instruments at the North Pole

Researchers at Oak Ridge National Laboratory were part of an international team that collected a treasure trove of data measuring precipitation, air particles, cloud patterns and the exchange of energy between the atmosphere and the sea ice.

UTK researchers used neutron probes at ORNL to confirm established fundamental chemical rules can also help understand and predict atomic movements and distortions in materials when disorder is introduced, as arrows show. Credit: Eric O’Quinn/UTK

Pauling’s Rules is the standard model used to describe atomic arrangements in ordered materials. Neutron scattering experiments at Oak Ridge National Laboratory confirmed this approach can also be used to describe highly disordered materials.

Suman Debnath is using simulation algorithms to accelerate understanding of the modern power grid and enhance its reliability and resilience. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Planning for a digitized, sustainable smart power grid is a challenge to which Suman Debnath is using not only his own applied mathematics expertise, but also the wider communal knowledge made possible by his revival of a local chapter of the IEEE professional society.

The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

Scientists synthesized graphene nanoribbons (yellow) on a titanium dioxide substrate (blue). The lighter ends show magnetic states. Inset: The ends have up and down spin, ideal for creating qubits. Credit: ORNL, U.S. Dept. of Energy

An international multi-institution team of scientists has synthesized graphene nanoribbons – ultrathin strips of carbon atoms – on a titanium dioxide surface using an atomically precise method that removes a barrier for custom-designed carbon