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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

 Caption: This computer-generated image of the JET tokamak shows what one would see if its walls were transparent, revealing the plasma inside. Credit: UK Atomic Energy Authority

A new fusion record was announced February 9 in the United Kingdom: At the Joint European Torus, or JET, the team documented the generation of 59 megajoules of sustained fusion energy, more than doubling the

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

Biopsy from the tubular esophagus showing incomplete intestinal metaplasia, goblet cells with interposed cells having gastric foveolar-type mucin consistent with Barrett esophagus. Negative for dysplasia. H&E stain. Credit: Creative Commons

A team including researchers from the Department of Energy’s Oak Ridge National Laboratory has developed a digital tool to better monitor a condition known as Barrett’s esophagus, which affects more than 3 million people in the United States.

Larry Baylor, left, and Andrew Lupini have been elected fellows of the American Physical Society. Credit: ORNL, U.S. Dept. of Energy

ORNL's Larry Baylor and Andrew Lupini have been elected fellows of the American Physical Society.

The first central solenoid module arrived at the ITER site in St. Paul-lez-Durance, France on Sept. 9. Credit: ITER Organization

Staff at Oak Ridge National Laboratory organized transport for a powerful component that is critical to the world’s largest experiment, the international ITER project.

Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.

As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.

Researchers studying secondary metabolites in the fungus Aspergillus flavus, pictured, found unique mixes of metabolites corresponding to genetically distinct populations. The finding suggests local environmental conditions play a key role in secondary metabolite production, influencing the discovery of drugs and other useful compounds. Credit: Tomás Allen Rush/ORNL, U.S. Dept. of Energy.

Scientists at ORNL and the University of Wisconsin–Madison have discovered that genetically distinct populations within the same species of fungi can produce unique mixes of secondary metabolites, which are organic compounds with applications in

For the first time in 25 years, scientists will use deuterium and tritium to create a plasma inside the chamber of the Joint European Torus in the United Kingdom to study nuclear fusion. As in the earlier experiments, diagnostics systems developed by ORNL will play a key role in monitoring the plasma. Credit: EUROfusion

Equipment and expertise from Oak Ridge National Laboratory will allow scientists studying fusion energy and technologies to acquire crucial data during landmark fusion experiments in Europe. 

The REVISE-II modeling tool developed at ORNL supports decision-making for electric vehicle charging infrastructure development along interstate highways in support of intercity travel. Credit: Jason Richards/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory have developed a nationwide modeling tool to help infrastructure planners decide where and when to locate electric vehicle charging stations along interstate highways. The goal is to encourage the adoption of EVs for cross-country travel.