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Media Contacts
![The configurational ensemble (a collection of 3D structures) of an intrinsically disordered protein, the N-terminal of c-Src kinase, which is a major signaling protein in humans. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2019-10/Petridis-PNAS-9.19.19-full%5B3%5D.png?h=d2706590&itok=7rUw2wkM)
Using the Titan supercomputer and the Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory, scientists have created the most accurate 3D model yet of an intrinsically disordered protein, revealing the ensemble of its atomic-level structures.
![Ryan Kerekes is leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory. Photos by Genevieve Martin, ORNL. Ryan Kerekes is leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory. Photos by Genevieve Martin, ORNL.](/sites/default/files/styles/list_page_thumbnail/public/Ryan%20Kerekes%20Profile%20lab1_0.jpg?itok=btnfhbaJ)
As leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory, Kerekes heads an accelerated lab-directed research program to build virtual models of critical infrastructure systems like the power grid that can be used to develop ways to detect and repel cyber-intrusion and to make the network resilient when disruption occurs.
![ORNL Image](/sites/default/files/styles/list_page_thumbnail/public/2017-S00094_2.jpg?itok=ZGWBnMOv)
Researchers used neutrons to probe a running engine at ORNL’s Spallation Neutron Source