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Media Contacts
![ORNL metabolic engineer Adam Guss develops genetic tools to modify microbes that can perform a range of processes needed to create sustainable biofuels and bioproducts. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-08/2021-P05224.jpg?h=8f9cfe54&itok=_5e3ckBD)
As a metabolic engineer at Oak Ridge National Laboratory, Adam Guss modifies microbes to perform the diverse processes needed to make sustainable biofuels and bioproducts.
![ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P05683_0.jpg?h=4c5cadcc&itok=FSVdbEYP)
In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.
![Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL](/sites/default/files/styles/list_page_thumbnail/public/2021-05/Putida_forAdam_2clr_2.jpg?h=71f44bf2&itok=8u0ZVufx)
A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.
![Researchers Adam Guss and Melissa Tumen-Velasquez work with microbes to understand how the organisms consume plastics and break them into chemical components that can be used to make higher-value products.](/sites/default/files/styles/list_page_thumbnail/public/2020-11/2020-P17629.jpg?h=98541007&itok=54ubVna4)
From soda bottles to car bumpers to piping, electronics, and packaging, plastics have become a ubiquitous part of our lives.
![ORNL scientists have optimized the Pseudomonas putida bacterium to digest five of the most abundant components of lignocellulosic biomass simultaneously, supporting a highly efficient conversion process to create renewable fuels and chemicals from plants. Credit: Alli Werner/NREL,U.S. Dept of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-09/P%20Putida_1.png?h=5c41473f&itok=aqfqpwbE)
ORNL scientists have modified a single microbe to simultaneously digest five of the most abundant components of lignocellulosic biomass, a big step forward in the development of a cost-effective biochemical conversion process to turn plants into
![A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.](/sites/default/files/styles/list_page_thumbnail/public/2019-09/bacteria_combinedwlabels1.png?h=f0ebf81d&itok=S-lziAuh)
Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.