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ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Protein domain common to plants and animals plays role in COVID-19 infection

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

ORNL-led team designs molecule to disrupt SARS-CoV-2 infection

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

The next generation of the Center for Bioenergy Innovation will pursue an accelerated feedstock-to-fuels approach for the efficient, economic production of sustainable jet fuel. Credit: ORNL, U.S. Dept. of Energy

DOE funds next-generation Center for Bioenergy Innovation to advance renewable jet fuel

The Center for Bioenergy Innovation has been renewed by the Department of Energy as one of four bioenergy research centers across the nation to advance robust, economical production of plant-based fuels and chemicals.

An illustration of the long-term evolution likely to occur as rising temperatures and subsequent thawing of frozen Arctic soils affects the northern Alaska tundra, as predicted by a high-performance model created by Oak Ridge National Laboratory. Credit: Adam Malin and Ethan Coon, ORNL/U.S. Dept. of Energy

Study finds sinking tundra surface unlikely to trigger runaway permafrost thaw

Oak Ridge National Laboratory scientists set out to address one of the biggest uncertainties about how carbon-rich permafrost will respond to gradual sinking of the land surface as temperatures rise.

Jason Gardner, Sandra Davern and Peter Thornton have been elected fellows of AAAS. Credit: Laddy Fields/ORNL, U.S. Dept. of Energy

AAAS elects three ORNL scientists as fellows

Three scientists from the Department of Energy’s Oak Ridge National Laboratory have been elected fellows of the American Association for the Advancement of Science, or AAAS.

Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Computational study finds genetic links, therapy targets for varicose veins

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.

Seven scientists at the Department of Energy’s Oak Ridge National Laboratory have been named Battelle Distinguished Inventors, in recognition of their obtaining 14 or more patents during their careers at the lab. Credit: ORNL, U.S. Dept. of Energy

Seven scientists named Battelle Distinguished Inventors

Seven scientists at the Department of Energy’s Oak Ridge National Laboratory have been named Battelle Distinguished Inventors, in recognition of their obtaining 14 or more patents during their careers at the lab.

Iron content gives a reddish hue to an area of ponded water in the Arctic permafrost. ORNL scientists are exploring the importance of the iron cycle on how greenhouse gases are released from thawing Arctic soils. Credit: David Graham/ORNL, U.S. Dept. of Energy

Scientists find iron cycling key to permafrost greenhouse gas emissions

The interaction of elemental iron with the vast stores of carbon locked away in Arctic soils is key to how greenhouse gases are emitted during thawing and should be included in models used to predict Earth’s climate.

Jack Cahill of ORNL’s Biosciences Division is developing new techniques to view and measure the previously unseen to better understand important chemical processes at play in plant-microbe interactions and in human health. In this photo, Cahill is positioning a rhizosphere-on-a-chip platform for imaging by mass spectrometry. Credit: Carlos Jones/ORNL, U.S. Dept of Energy

Jack Cahill: Evidence of things unseen

John “Jack” Cahill is out to illuminate previously unseen processes with new technology, advancing our understanding of how chemicals interact to influence complex systems whether it’s in the human body or in the world beneath our feet.

Eight ORNL scientists are among the world’s most highly cited researchers, Credit: Butch Newton/ORNL, U.S. Dept. of Energy

Eight ORNL scientists among world’s most cited researchers

Eight ORNL scientists are among the world’s most highly cited researchers, according to a bibliometric analysis conducted by the scientific publication analytics firm Clarivate.