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Jennifer Morrell-Falvey leads the Molecular and Cellular Imaging group at ORNL, advancing new insights in several scientific areas, including the interactions between plants and microbes that influence ecosystem health and carbon cycling. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Jennifer Morrell-Falvey’s interest in visualizing the science behind natural processes was what drew her to ORNL in what she expected to be a short stint some 18 years ago. 

ORNL scientists created a new microbial trait mapping process that improves on classical protoplast fusion techniques to identify the genes that trigger desirable genetic traits like improved biomass processing. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy. Reprinted with the permission of Oxford University Press, publisher of Nucleic Acids Research

ORNL scientists had a problem mapping the genomes of bacteria to better understand the origins of their physical traits and improve their function for bioenergy production.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An artist's rendering of the Ultium Cells battery cell production facility to be built in Spring Hill, Tennessee, which will employ 1,300 people. Recognizing the unique expertise of their organizations, ORNL, TVA, and the Tennessee Department of Economic and Community Development have been working together for several years to bring startups developing battery technologies for EVs and established automotive firms to Tennessee. Credit: Ultium Cells

ORNL, TVA and TNECD were recognized by the Federal Laboratory Consortium for their impactful partnership that resulted in a record $2.3 billion investment by Ultium Cells, a General Motors and LG Energy Solution joint venture, to build a battery cell manufacturing plant in Spring Hill, Tennessee.

ORNL’s Marie Kurz examines the many factors affecting the health of streams and watersheds. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Spanning no less than three disciplines, Marie Kurz’s title — hydrogeochemist — already gives you a sense of the collaborative, interdisciplinary nature of her research at ORNL.

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals. Credit: ORNL, U.S. Dept. of Energy

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals.

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.

Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers. Credit: ORNL, U.S. Dept. of Energy

Ten scientists from the Department of Energy’s Oak Ridge National Laboratory are among the world’s most highly cited researchers, according to a bibliometric analysis conducted by the scientific publication analytics firm Clarivate.

Researchers gained new insights into the mechanisms some methane-feeding bacteria called methanotrophs (pictured) use to break down the toxin methylmercury. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy; Jeremy Semrau/Univ. of Michigan

A team led by ORNL and the University of Michigan have discovered that certain bacteria can steal an essential compound from other microbes to break down methane and toxic methylmercury in the environment.