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![A Co-Optima research team led by Oak Ridge National Laboratory’s Jim Szybist in collaboration with Argonne, Sandia and the National Renewable Energy Laboratory, created a merit function tool that evaluates six fuel properties and their impact on engine performance, giving the scientific community a guide to quickly evaluate biofuels. Credit: ORNL/U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-12/2017-P08539-2_0.jpg?h=b6236d98&itok=h0OT2BqC)
As ORNL’s fuel properties technical lead for the U.S. Department of Energy’s Co-Optimization of Fuel and Engines, or Co-Optima, initiative, Jim Szybist has been on a quest for the past few years to identify the most significant indicators for predicting how a fuel will perform in engines designed for light-duty vehicles such as passenger cars and pickup trucks.
![Enzyme activity during organophosphate poisoning](/sites/default/files/styles/list_page_thumbnail/public/2020-08/anecdote1_0.png?h=d1cb525d&itok=wpYYilBI)
Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.
![Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2020-07/2017-P06162Cropped.jpg?h=f1d4573a&itok=TrvR_opt)
Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology
![Suman Debnath](/sites/default/files/styles/list_page_thumbnail/public/2020-04/SumanDebnathThumb.jpg?h=38099c27&itok=_Eq7kvb6)
Suman Debnath, a researcher at ORNL, has been elevated to the grade of senior member of the Institute of Electrical and Electronics Engineers (IEEE).
![Coronavirus graphic](/sites/default/files/styles/list_page_thumbnail/public/2020-04/covid19_jh_0.png?h=d1cb525d&itok=PyngFUZw)
In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.
![Scientists created a novel polymer that is as effective as natural proteins in transporting protons through a membrane. Credit: ORNL/Jill Hemman](/sites/default/files/styles/list_page_thumbnail/public/2020-03/19-G01195_nature_feature_0.png?h=e4fbc3eb&itok=K8czXmTr)
Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.
![Starch granules](/sites/default/files/styles/list_page_thumbnail/public/2020-02/starchgranules.png?h=0c9ab501&itok=eLsE3JOx)
Scientists at the Department of Energy’s Oak Ridge National Laboratory have developed a new method to peer deep into the nanostructure of biomaterials without damaging the sample. This novel technique can confirm structural features in starch, a carbohydrate important in biofuel production.
![Examples from the ORNL Overhead Vehicle Dataset, generated with images captured by GRIDSMART cameras. Image: Thomas Karnowski/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2020-02/truckgrid-corrected-1024x745.png?h=bc62b519&itok=HY9xstgl)
Each year, approximately 6 billion gallons of fuel are wasted as vehicles wait at stop lights or sit in dense traffic with engines idling, according to US Department of Energy estimates.
![The students analyzed diatom images like this one to compare wild and genetically modified strains of these organisms. Credit: Alison Pawlicki/Oak Ridge National Laboratory, US Department of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2019-11/RI4362007.png?h=37702503&itok=9lQReLRe)
Students often participate in internships and receive formal training in their chosen career fields during college, but some pursue professional development opportunities even earlier.
![A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.](/sites/default/files/styles/list_page_thumbnail/public/2019-09/bacteria_combinedwlabels1.png?h=f0ebf81d&itok=S-lziAuh)
Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.