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ORNL’s Adam Guss and colleagues used synthetic biology to develop a custom microbe capable of converting deconstructed mixed plastic waste into valuable new materials. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists working on a solution for plastic waste have developed a two-step chemical and biological process to break down and upcycle mixed plastics into valuable bioproducts.

Distinguished staff fellow Gang Seob “GS” Jung knew from an early age he wanted to be a scientist. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Gang Seob “GS” Jung has known from the time he was in middle school that he was interested in science.

Earth Day

Tackling the climate crisis and achieving an equitable clean energy future are among the biggest challenges of our time. 

ORNL scientists created a new microbial trait mapping process that improves on classical protoplast fusion techniques to identify the genes that trigger desirable genetic traits like improved biomass processing. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy. Reprinted with the permission of Oxford University Press, publisher of Nucleic Acids Research

ORNL scientists had a problem mapping the genomes of bacteria to better understand the origins of their physical traits and improve their function for bioenergy production.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

Carrie Eckert

Carrie Eckert applies her skills as a synthetic biologist at ORNL to turn microorganisms into tiny factories that produce a variety of valuable fuels, chemicals and materials for the growing bioeconomy.

ORNL metabolic engineer Adam Guss develops genetic tools to modify microbes that can perform a range of processes needed to create sustainable biofuels and bioproducts. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

As a metabolic engineer at Oak Ridge National Laboratory, Adam Guss modifies microbes to perform the diverse processes needed to make sustainable biofuels and bioproducts.

ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.

Researchers Adam Guss and Melissa Tumen-Velasquez work with microbes to understand how the organisms consume plastics and break them into chemical components that can be used to make higher-value products.

From soda bottles to car bumpers to piping, electronics, and packaging, plastics have become a ubiquitous part of our lives. 

A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.