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Artificial intelligence is becoming an increasingly valuable tool for ORNL researchers tackling the many mysteries of cancer. Credit: Getty Images.

A team of researchers from ORNL was recognized by the National Cancer Institute in March for their unique contributions in the fight against cancer.

Phil Snyder

When virtually unlimited energy from fusion becomes a reality on Earth, Phil Snyder and his team will have had a hand in making it happen.

Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

ORNL fusion technology scientist Tim Bigelow, right, stands near the control console in ORNL’s  fusion control room with Matt Houde of Quaise Energy. Their partnership aims to tackle technical challenges with the Millimeter Wave Drilling System that Quaise has developed. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy.

Researchers in the geothermal energy industry are joining forces with fusion experts at ORNL to repurpose gyrotron technology, a tool used in fusion. Gyrotrons produce high-powered microwaves to heat up fusion plasmas.

ORNL’s Bruce Pint, left, and Marie Romedenne review experiment results. Credit: ORNL, U.S. Dept. of Energy

Practical fusion energy is not just a dream at ORNL. Experts in fusion and material science are working together to develop solutions that will make a fusion pilot plant — and ultimately carbon-free, abundant fusion electricity — possible.

A team of fusion scientists and engineers stand in front of ORNL’s Helium Flow Loop device. From back left to front right: Chris Crawford, Fayaz Rasheed, Joy Fan, Michael Morrow, Charles Kessel, Adam Carroll, and Cody Wiggins. Not pictured: Dennis Youchison and Monica Gehrig. Credit: Carlos Jones/ORNL.

To achieve practical energy from fusion, extreme heat from the fusion system “blanket” component must be extracted safely and efficiently. ORNL fusion experts are exploring how tiny 3D-printed obstacles placed inside the narrow pipes of a custom-made cooling system could be a solution for removing heat from the blanket.

The ORNL researchers’ findings may enable better detection of uranium tetrafluoride hydrate, a little-studied byproduct of the nuclear fuel cycle, and better understanding of how environmental conditions influence the chemical behavior of fuel cycle materials. Credit: Kevin Pastoor/Colorado School of Mines

ORNL researchers used the nation’s fastest supercomputer to map the molecular vibrations of an important but little-studied uranium compound produced during the nuclear fuel cycle for results that could lead to a cleaner, safer world.

ORNL fusion scientist Elijah Martin is working with TAE Technologies to demonstrate the feasibility of field-reversed configuration reactors, a possible alternative to the traditional tokamak-based devices. Credit: ORNL.

ORNL manages the Innovation Network for Fusion Energy Program, or INFUSE, with Princeton Plasma Physics Laboratory, to help the private sector find solutions to technical challenges that need to be resolved to make practical fusion energy a reality.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.