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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Kevin Robb, a staff scientist at the Department of Energy’s Oak Ridge National Laboratory, is taking what he learned from developing the Liquid Salt Test Loop—a key tool in deploying molten salt technology applications

Thanks in large part to developing and operating a facility for testing molten salt reactor (MSR) technologies, nuclear experts at the Energy Department’s Oak Ridge National Laboratory (ORNL) are now tackling the next generation of another type of clean energy—concentrating ...

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

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For the past six years, some 140 scientists from five institutions have traveled to the Arctic Circle and beyond to gather field data as part of the Department of Energy-sponsored NGEE Arctic project. This article gives insight into how scientists gather the measurements that inform t...