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Scientists created a novel polymer that is as effective as natural proteins in transporting protons through a membrane. Credit: ORNL/Jill Hemman

Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.

Starch granules

Scientists at the Department of Energy’s Oak Ridge National Laboratory have developed a new method to peer deep into the nanostructure of biomaterials without damaging the sample. This novel technique can confirm structural features in starch, a carbohydrate important in biofuel production.

The image visualizes how the team’s multitask convolutional neural network classifies primary cancer sites. Image credit: Hong-Jun Yoon/ORNL

As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.

Liane Russell

A select group gathered on the morning of Dec. 20 at the Department of Energy’s Oak Ridge National Laboratory for a symposium in honor of Liane B. Russell, the renowned ORNL mammalian geneticist who died in July.

As part of DOE’s HPC4Mobility initiative ORNL researchers developed machine learning algorithms that can control smart traffic lights at intersections to facilitate the smooth flow of traffic and increase fuel efficiency.

A modern, healthy transportation system is vital to the nation’s economic security and the American standard of living. The U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) is engaged in a broad portfolio of scientific research for improved mobility

Tyler Gerczak, a materials scientist at Oak Ridge National Laboratory, is focused on post-irradiation examination and separate effects testing of current fuels for light water reactors and advanced fuel types that could be used in future nuclear systems. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

Ask Tyler Gerczak to find a negative in working at the Department of Energy’s Oak Ridge National Laboratory, and his only complaint is the summer weather. It is not as forgiving as the summers in Pulaski, Wisconsin, his hometown.

Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

Rose Ruther and Jagjit Nanda have been collaborating to develop a membrane for a low-cost redox flow battery for grid-scale energy storage.

Oak Ridge National Laboratory scientists have developed a crucial component for a new kind of low-cost stationary battery system utilizing common materials and designed for grid-scale electricity storage. Large, economical electricity storage systems can benefit the nation’s grid ...