Skip to main content
Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

Alex Johs at ORNL's Spallation Neutron Source

Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at Oak Ridge National Laboratory bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.

Coexpression_hi-res_image[1].jpg

While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Ryan Kerekes is leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory. Photos by Genevieve Martin, ORNL.

As leader of the RF, Communications, and Cyber-Physical Security Group at Oak Ridge National Laboratory, Kerekes heads an accelerated lab-directed research program to build virtual models of critical infrastructure systems like the power grid that can be used to develop ways to detect and repel cyber-intrusion and to make the network resilient when disruption occurs.

ORNL Image

For the past six years, some 140 scientists from five institutions have traveled to the Arctic Circle and beyond to gather field data as part of the Department of Energy-sponsored NGEE Arctic project. This article gives insight into how scientists gather the measurements that inform t...

ORNL Director Thomas Zacharia (center, seated) visited Robertsville Middle School to present a check in support of the school’s CubeSat efforts.

Last November a team of students and educators from Robertsville Middle School in Oak Ridge and scientists from Oak Ridge National Laboratory submitted a proposal to NASA for their Cube Satellite Launch Initiative in hopes of sending a student-designed nanosatellite named RamSat into...