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The DEMAND single crystal diffractometer at the High Flux Isotope Reactor, or HFIR, is the latest neutron instrument at the Department of Energy’s Oak Ridge National Laboratory to be equipped with machine learning-assisted software, called ReTIA. Credit: Jeremy Rumsey/ORNL, U.S. Dept. of Energy

Neutron experiments can take days to complete, requiring researchers to work long shifts to monitor progress and make necessary adjustments. But thanks to advances in artificial intelligence and machine learning, experiments can now be done remotely and in half the time.

Madhavi Martin portrait image

Madhavi Martin brings a physicist’s tools and perspective to biological and environmental research at the Department of Energy’s Oak Ridge National Laboratory, supporting advances in bioenergy, soil carbon storage and environmental monitoring, and even helping solve a murder mystery.

Clouds of gray smoke in the lower left are funneled northward from wildfires in Western Canada, reaching the edge of the sea ice covering the Arctic Ocean. A second path of thick smoke is visible at the top center of the image, emanating from wildfires in the boreal areas of Russia’s Far East, in this image captured on July 13, 2023. Credit: NASA MODIS

Wildfires have shaped the environment for millennia, but they are increasing in frequency, range and intensity in response to a hotter climate. The phenomenon is being incorporated into high-resolution simulations of the Earth’s climate by scientists at the Department of Energy’s Oak Ridge National Laboratory, with a mission to better understand and predict environmental change.

Jerry Parks leads the Molecular Biophysics group at ORNL, leveraging his expertise in computational chemistry and bioinformatics to unlock the inner workings of proteins—molecules that govern cellular structure and function and are essential to life. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

When reading the novel Jurassic Park as a teenager, Jerry Parks found the passages about gene sequencing and supercomputers fascinating, but never imagined he might someday pursue such futuristic-sounding science.

Researchers Melissa Cregger, left, and Xiaohan Yang examine plants in an ORNL greenhouse where biosensors are installed to accelerate plant transformations. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy.

Nature-based solutions are an effective tool to combat climate change triggered by rising carbon emissions, whether it’s by clearing the skies with bio-based aviation fuels or boosting natural carbon sinks.

NASA scientist Andrew Needham used the MARS neutron imaging instrument at Oak Ridge National Laboratory to study moon rock samples brought back from the Apollo missions. Credit: Jeremy Rumsey/ORNL, U.S. Dept. of Energy

How did we get from stardust to where we are today? That’s the question NASA scientist Andrew Needham has pondered his entire career.

Jack Cahill of ORNL’s Biosciences Division is developing new techniques to view and measure the previously unseen to better understand important chemical processes at play in plant-microbe interactions and in human health. In this photo, Cahill is positioning a rhizosphere-on-a-chip platform for imaging by mass spectrometry. Credit: Carlos Jones/ORNL, U.S. Dept of Energy

John “Jack” Cahill is out to illuminate previously unseen processes with new technology, advancing our understanding of how chemicals interact to influence complex systems whether it’s in the human body or in the world beneath our feet.

Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

Scientists at ORNL have created a rhizosphere-on-a-chip research platform, a miniaturized environment to study the ecosystem around poplar tree roots for insights into plant health and soil carbon sequestration. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Scientists at ORNL have created a miniaturized environment to study the ecosystem around poplar tree roots for insights into plant health and soil carbon sequestration.

Samarthya Bhagia examines a sample of a thermoplastic composite material additively manufactured using poplar wood and polylactic acid. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Chemical and environmental engineer Samarthya Bhagia is focused on achieving carbon neutrality and a circular economy by designing new plant-based materials for a range of applications from energy storage devices and sensors to environmentally friendly bioplastics.