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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

CO2 release by mild heating of the BIG-bicarbonate solid. The released CO2 gas is trapped in the orange balloon, while the released water vapors are trapped by condensation in the ice-cooled U-shaped tube. Credit: Neil J. Williams and Erick Holguin.

Scientists at the Department of Energy’s Oak Ridge National Laboratory (ORNL) have developed a process that could remove CO2 from coal-burning power plant emissions in a way that is similar to how soda lime works in scuba diving rebreathers. Their research, published January 31 in...

From left, Amit Naskar, Ngoc Nguyen and Christopher Bowland in ORNL’s Carbon and Composites Group bring a new capability—structural health monitoring—to strong, lightweight materials promising for transportation applications.

Carbon fiber composites—lightweight and strong—are great structural materials for automobiles, aircraft and other transportation vehicles. They consist of a polymer matrix, such as epoxy, into which reinforcing carbon fibers have been embedded. Because of differences in the mecha...

Rose Ruther and Jagjit Nanda have been collaborating to develop a membrane for a low-cost redox flow battery for grid-scale energy storage.

Oak Ridge National Laboratory scientists have developed a crucial component for a new kind of low-cost stationary battery system utilizing common materials and designed for grid-scale electricity storage. Large, economical electricity storage systems can benefit the nation’s grid ...

The electromagnetic isotope separator system operates by vaporizing an element such as ruthenium into the gas phase, converting the molecules into an ion beam, and then channeling the beam through magnets to separate out the different isotopes.

A tiny vial of gray powder produced at the Department of Energy’s Oak Ridge National Laboratory is the backbone of a new experiment to study the intense magnetic fields created in nuclear collisions.

From left, ORNL’s Rick Lowden, Chris Bryan and Jim Kiggans were troubled that target discs of a material needed to produce Mo-99 using an accelerator could deform after irradiation and get stuck in their holder.

“Made in the USA.” That can now be said of the radioactive isotope molybdenum-99 (Mo-99), last made in the United States in the late 1980s. Its short-lived decay product, technetium-99m (Tc-99m), is the most widely used radioisotope in medical diagnostic imaging. Tc-99m is best known ...

Arjun Shankar

The field of “Big Data” has exploded in the blink of an eye, growing exponentially into almost every branch of science in just a few decades. Sectors such as energy, manufacturing, healthcare and many others depend on scalable data processing and analysis for continued in...

ORNL’s Xiahan Sang unambiguously resolved the atomic structure of MXene, a 2D material promising for energy storage, catalysis and electronic conductivity. Image credit: Oak Ridge National Laboratory, U.S. Dept. of Energy; photographer Carlos Jones

Researchers have long sought electrically conductive materials for economical energy-storage devices. Two-dimensional (2D) ceramics called MXenes are contenders. Unlike most 2D ceramics, MXenes have inherently good conductivity because they are molecular sheets made from the carbides ...

Pellet selector

When it’s up and running, the ITER fusion reactor will be very big and very hot, with more than 800 cubic meters of hydrogen plasma reaching 170 million degrees centigrade. The systems that fuel and control it, on the other hand, will be small and very cold. Pellets of frozen gas will be shot int...