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The configurational ensemble (a collection of 3D structures) of an intrinsically disordered protein, the N-terminal of c-Src kinase, which is a major signaling protein in humans. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy.

Using the Titan supercomputer and the Spallation Neutron Source at the Department of Energy’s Oak Ridge National Laboratory, scientists have created the most accurate 3D model yet of an intrinsically disordered protein, revealing the ensemble of its atomic-level structures.

Summit supercomputer

Processes like manufacturing aircraft parts, analyzing data from doctors’ notes and identifying national security threats may seem unrelated, but at the U.S. Department of Energy’s Oak Ridge National Laboratory, artificial intelligence is improving all of these tasks.

Water and energy are inextricably linked, yet in our 20th-century water systems we use freshwater once then throw it away. With innovations designed to enhance desalination technologies, agricultural runoff, produced water from industry, and inland brackish groundwater that are now seen as untreatable could all be sources of clean, safe, and affordable water.

The National Alliance for Water Innovation, a partnership of the Department of Energy’s Oak Ridge National Laboratory, other national labs, university and private sector partners, has been awarded a five-year, $100 million Energy-Water Desalination Hub by DOE to address water security issues in the United States.

low-cost material can be used as an additive to increase thermal insulation performance

Quanex Building Products has signed a non-exclusive agreement to license a method to produce insulating material from ORNL. The low-cost material can be used as an additive to increase thermal insulation performance and improve energy efficiency when applied to a variety of building products.

A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.

Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.

As part of DOE’s HPC4Mobility initiative ORNL researchers developed machine learning algorithms that can control smart traffic lights at intersections to facilitate the smooth flow of traffic and increase fuel efficiency.

A modern, healthy transportation system is vital to the nation’s economic security and the American standard of living. The U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) is engaged in a broad portfolio of scientific research for improved mobility

Ethan Coon uses math and computational science to model the flow of above and belowground water in watersheds.

As a computational hydrologist at Oak Ridge National Laboratory, Ethan Coon combines his talent for math with his love of coding to solve big science questions about water quality, water availability for energy production, climate change, and the

Lighting up liquid crystals

Researchers used neutron scattering at Oak Ridge National Laboratory’s Spallation Neutron Source to probe the structure of a colorful new material that may pave the way for improved sensors and vivid displays.

Layering on the strength

A team including Oak Ridge National Laboratory and University of Tennessee researchers demonstrated a novel 3D printing approach called Z-pinning that can increase the material’s strength and toughness by more than three and a half times compared to conventional additive manufacturing processes.

Project bridges compute staff, resources at ORNL and VA health data to speed suicide risk screening for US veterans. Image Credit: Carlos Jones, ORNL

More than 6,000 veterans died by suicide in 2016, and from 2005 to 2016, the rate of veteran suicides in the United States increased by more than 25 percent.