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Media Contacts
![ORNL’s biosensor system reveals CRISPR activity in poplar plants, which glow bright green under ultraviolet light, compared to normal plants, which appear red. Credit: Guoliang Yuan/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-12/GFPuv.png?h=b657ac0b&itok=Qs2Z_btM)
Detecting the activity of CRISPR gene editing tools in organisms with the naked eye and an ultraviolet flashlight is now possible using technology developed at ORNL.
![Carrie Eckert](/sites/default/files/styles/list_page_thumbnail/public/2021-11/2021-P08048.jpg?h=fdb72c6d&itok=pWcXR26-)
Carrie Eckert applies her skills as a synthetic biologist at ORNL to turn microorganisms into tiny factories that produce a variety of valuable fuels, chemicals and materials for the growing bioeconomy.
![ORNL metabolic engineer Adam Guss develops genetic tools to modify microbes that can perform a range of processes needed to create sustainable biofuels and bioproducts. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-08/2021-P05224.jpg?h=8f9cfe54&itok=_5e3ckBD)
As a metabolic engineer at Oak Ridge National Laboratory, Adam Guss modifies microbes to perform the diverse processes needed to make sustainable biofuels and bioproducts.
![ORNL’s Josh Michener, a microbiologist and metabolic engineer, led the discovery of a useful new enzyme that breaks down stubborn bonds in lignin, a polymer found in plants that typically becomes waste during bioconversion. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/2019-P05683_0.jpg?h=4c5cadcc&itok=FSVdbEYP)
In a step toward increasing the cost-effectiveness of renewable biofuels and bioproducts, scientists at ORNL discovered a microbial enzyme that degrades tough-to-break bonds in lignin, a waste product of biorefineries.
![Scientists genetically engineered bacteria for itaconic acid production, creating dynamic controls that separate microbial growth and production phases for increased efficiency and acid yield. Credit: NREL](/sites/default/files/styles/list_page_thumbnail/public/2021-05/Putida_forAdam_2clr_2.jpg?h=71f44bf2&itok=8u0ZVufx)
A research team led by Oak Ridge National Laboratory bioengineered a microbe to efficiently turn waste into itaconic acid, an industrial chemical used in plastics and paints.
![A new method uses E. coli to generate DNA with methylation patterns that target microbes recognize and accept as their own, facilitating customization of microbes for biofuels production.](/sites/default/files/styles/list_page_thumbnail/public/2019-09/bacteria_combinedwlabels1.png?h=f0ebf81d&itok=S-lziAuh)
Scientists at the US Department of Energy’s Oak Ridge National Laboratory have demonstrated a method to insert genes into a variety of microorganisms that previously would not accept foreign DNA, with the goal of creating custom microbes to break down plants for bioenergy.
![At the salt–metal interface, thermodynamic forces drive chromium from the bulk of a nickel alloy, leaving a porous, weakened layer. Impurities in the salt drive further corrosion of the structural material. Credit: Stephen Raiman/Oak Ridge National Labora At the salt–metal interface, thermodynamic forces drive chromium from the bulk of a nickel alloy, leaving a porous, weakened layer. Impurities in the salt drive further corrosion of the structural material. Credit: Stephen Raiman/Oak Ridge National Labora](/sites/default/files/styles/list_page_thumbnail/public/story%20tip%20image%20BW%20only.jpg?itok=Vbc0iTLt)
Oak Ridge National Laboratory scientists analyzed more than 50 years of data showing puzzlingly inconsistent trends about corrosion of structural alloys in molten salts and found one factor mattered most—salt purity.