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Oak Ridge National Laboratory bioinformatics researcher Dan Jacobson plugs AI, deep learning into biosystems.
Dan Jacobson is illuminating the workings of biological systems from the molecular scale up by leveraging Oak Ridge National Laboratory’s supercomputing resources to create machine- and deep-learning techniques more easily understood by humans—an evolving field called explainable...
The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers. A team of researchers led by the Department of Energy’s Oak Ridge National Laboratory used neutro...
Germina Ilas (left) and Ian Gauld review spent fuel data entries in the SFCOMPO 2.0 database.
Oak Ridge National Laboratory provided significant contributions and coordination in the development of the Nuclear Energy Agency’s (NEA’s) recently released Spent Fuel Isotopic Composition (SFCOMPO) 2.0—the world’s largest open database for spent
In a model of a 1.6 liter engine cylinder, liquid fuel (shown in red and orange) is converted to fuel vapor under high temperatures during ignition. Image courtesy of Ronald Grover.

Most car owners in the United States do not think twice about passing over the diesel pump at the gas station. Instead, diesel fuel mostly powers our shipping trucks, boats, buses, and generators—and that is because diesel engines are about 10 percent more fuel-efficient than gaso...

A conceptual illustration of proton-proton fusion in which two protons fuse to form a deuteron. Image courtesy of William Detmold.

Nuclear physicists are using the nation’s most powerful supercomputer, Titan, at the Oak Ridge Leadership Computing Facility to study particle interactions important to energy production in the Sun and stars and to propel the search for new physics discoveries Direct calculatio...

ORNL and EPRI built an enclosed welding system in a hot cell of ORNL’s Radiochemical Engineering Development Center. C. Scott White (ORNL) performs operations with remotely controlled manipulators and cameras.

Scientists of the Department of Energy’s Light Water Reactor Sustainability Program (LWRS) and partners from the Electric Power Research Institute (EPRI) have conducted the first weld tests to repair highly irradiated materials at DOE’s Oak Ridge National Laboratory.

Yarom Polsky

Yarom Polsky’s diverse background in private and public-sector research has given him a knack for recognizing opportunities to advance the state-of-the-art, and he parlays that knowledge into successful innovation as an engineer, group leader, and 

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A team led by the Department of Energy’s Oak Ridge National Laboratory has uncovered how certain soil microbes cope in a phosphorus-poor environment to survive in a tropical ecosystem. Their novel approach could be applied in other ecosystems to study various nutrient limitations and inform agriculture and terrestrial biosphere modeling.
ORNL’s Steven Young (left) and Travis Johnston used Titan to prove the design and training of deep learning networks could be greatly accelerated with a capable computing system.

A team of researchers from the Department of Energy’s Oak Ridge National Laboratory has married artificial intelligence and high-performance computing to achieve a peak speed of 20 petaflops in the generation and training of deep learning networks on the