Skip to main content
Colorized micrograph of lily pollen

Oak Ridge National Laboratory researchers have built a novel microscope that provides a “chemical lens” for viewing biological systems including cell membranes and biofilms.

Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

ORNL’s Bianca Haberl and Amy Elliott hold 3D-printed collimators — an invention that has been licensed to ExOne, a leading binder jet 3D printer company. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory has licensed a novel method to 3D print components used in neutron instruments for scientific research to the ExOne Company, a leading maker of binder jet 3D printing technology.

Computing – Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the

Transformational Challenge Reactor Demonstration items

Researchers at the Department of Energy’s Oak Ridge National Laboratory are refining their design of a 3D-printed nuclear reactor core, scaling up the additive manufacturing process necessary to build it, and developing methods

Researchers at DOE’s Manufacturing Demonstration Facility at ORNL developed a reusable face mask prototype with injection molding that will enable industry to rapidly manufacture. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

In the fight against the COVID-19 pandemic, it’s a race against the clock not only to find a vaccine but also to supply healthcare workers with life-saving equipment such as face shields, masks and test kits.

ORNL’s Brian Post

Brian Post, a researcher in large-scale additive manufacturing at ORNL, has been selected as a recipient of the 2020 Outstanding Young Manufacturing Engineer Award by SME. 

Coronavirus graphic

In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.

ORNL scientists are combining their expertise in environmental science, physics, sensors and additive manufacturing to create model fish for use in testing of hydropower turbine designs. The project supports healthy ecosystems and hydropower—the nation’s largest renewable energy resource. Photo credit: Oak Ridge National Laboratory, U.S. Dept. of Energy.

Hydropower developers must consider many factors when it comes time to license a new project or renew an existing one: How can environmental impacts be mitigated, including to fish populations?