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NellOne Therapeutics has licensed a drug delivery system from the Department of Energy’s Oak Ridge National Laboratory that is designed to transport therapeutics directly to cells infected by SARS-CoV-2, the virus causing COVID-19.

Data collection instruments at the North Pole

Researchers at Oak Ridge National Laboratory were part of an international team that collected a treasure trove of data measuring precipitation, air particles, cloud patterns and the exchange of energy between the atmosphere and the sea ice.

ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy

Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.

ORNL’s collaboration with Cincinati Children’s Hospital Medical Center will leverage the lab’s expertise in high-performance computing and safe, secure recordkeeping. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

There are more than 17 million veterans in the United States, and approximately half rely on the Department of Veterans Affairs for their healthcare.

The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

U.S. Department of Energy Deputy Secretary Mark Menezes (right) tours the DemeTECH N95 filter material production area with Xin Sun, ORNL interim associate laboratory director (center) and Craig Blue, ORNL advanced manufacturing program manager. Credit: US Dept. of Energy

A collaboration between the ORNL and a Florida-based medical device manufacturer has led to the addition of 500 jobs in the Miami area to support the mass production of N95 respirator masks.

Scientists synthesized graphene nanoribbons (yellow) on a titanium dioxide substrate (blue). The lighter ends show magnetic states. Inset: The ends have up and down spin, ideal for creating qubits. Credit: ORNL, U.S. Dept. of Energy

An international multi-institution team of scientists has synthesized graphene nanoribbons – ultrathin strips of carbon atoms – on a titanium dioxide surface using an atomically precise method that removes a barrier for custom-designed carbon

Emma Betters Thumbnail

Growing up in Florida, Emma Betters was fascinated by rockets and for good reason. Any time she wanted to see a space shuttle launch from NASA’s nearby Kennedy Space Center, all she had to do was sit on her front porch.

These fuel assembly brackets, manufactured by ORNL in partnership with Framatome and Tennessee Valley Authority, are the first 3D-printed safety-related components to be inserted into a nuclear power plant. Credit: Fred List/ORNL, U.S. Dept. of Energy

The Transformational Challenge Reactor, or TCR, a microreactor built using 3D printing and other new advanced technologies, could be operational by 2024.

An ORNL researcher holds a capsule of molten salt. Preliminary experiments seem to indicate that irradiation can slow corrosion of metal in liquid salt. Credit: ORNL, U.S. Dept. of Energy

Irradiation may slow corrosion of alloys in molten salt, a team of Oak Ridge National Laboratory scientists has found in preliminary tests.