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ORNL scientists created a new microbial trait mapping process that improves on classical protoplast fusion techniques to identify the genes that trigger desirable genetic traits like improved biomass processing. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy. Reprinted with the permission of Oxford University Press, publisher of Nucleic Acids Research

ORNL scientists had a problem mapping the genomes of bacteria to better understand the origins of their physical traits and improve their function for bioenergy production.

Scientists with the Center for Bioenergy Innovation at ORNL highlighted a hybrid approach that uses microbes and catalysis to convert cellulosic biomass into fuels suitable for aviation and other difficult-to-electrify sectors. Credit: ORNL, U.S. Dept. of Energy

The rapid pace of global climate change has added urgency to developing technologies that reduce the carbon footprint of transportation technologies, especially in sectors that are difficult to electrify.

Bryan Piatkowski is a Liane Russell Distinguished Fellow at ORNL developing a framework to better understand the genetic underpinnings of desirable plant traits so they may be used to create climate-resilient crops for food, bioenergy and carbon sequestration. Credit: Carlos Jones/ORNL, U.S. Dept of Energy.

Bryan Piatkowski, a Liane Russell Distinguished Fellow in the Biosciences Division at ORNL, is exploring the genetic pathways for traits such as stress tolerance in several plant species important for carbon sequestration

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

Scientists from LanzaTech, Northwestern University and Oak Ridge National Laboratory engineered a microbe, shown in light blue, to convert molecules of industrial waste gases, such as carbon dioxide and carbon monoxide, into acetone. The same microbe can also make isopropanol. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

A team of scientists from LanzaTech, Northwestern University and ORNL have developed carbon capture technology that harnesses emissions from industrial processes to produce acetone and isopropanol

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals. Credit: ORNL, U.S. Dept. of Energy

Three ORNL scientists have been elected fellows of the American Association for the Advancement of Science, or AAAS, the world’s largest general scientific society and publisher of the Science family of journals.

This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography.  Credit: Ada Sedova/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.