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Two hybrid poplar plants, middle and right, engineered with the PtrXB38 hub gene exhibited a drastic increase in root and callus formation compared with a wild-type control plant, left. Credit: Tao Yao/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists identified a gene “hotspot” in the poplar tree that triggers dramatically increased root growth. The discovery supports development of better bioenergy crops and other plants that can thrive in difficult conditions while storing more carbon belowground.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

ORNL researchers are developing a method to print low-cost, high-fidelity, customizable sensors for monitoring power grid equipment. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A method developed at Oak Ridge National Laboratory to print high-fidelity, passive sensors for energy applications can reduce the cost of monitoring critical power grid assets.

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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

Philip Bingham

Philip Bingham has two pieces of advice for researchers new to Oak Ridge National Laboratory: (1) develop a skill set that can be applied to multiple research areas, and (2) get out and meet folks across the lab. “The favorite part of my work is that I’ve done a lot of very diffe...

The sensors measure parameters like temperature, chemicals and electric grid elements for industrial and electrical applications. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

Brixon, Inc., has exclusively licensed a multiparameter sensor technology from the Department of Energy’s Oak Ridge National Laboratory. The integrated platform uses various sensors that measure physical and environmental parameters and respond to standard security applications.

A radiologist outfitted with the team’s head-mounted eye-tracking device examines a mammogram. Credit: Hong-Jun Yoon/Oak Ridge National Laboratory, U.S. Dept. of Energy

In an effort to reduce errors in the analyses of diagnostic images by health professionals, a team of researchers from the Department of Energy’s Oak Ridge National Laboratory has improved understanding of the cognitive processes 

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For decades, biologists have believed a key enzyme in plants had one function—produce amino acids, which are vital to plant survival and also essential to human diets. But for Wellington Muchero, Meng Xie and their colleagues, this enzyme does more than advertised. They had run a series of experiments on poplar plants that consistently revealed mutations in a structure of the life-sustaining enzyme that was not previously known to exist.

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A new process to identify certain microbes in women could be used to diagnose endometriosis without invasive surgery, even before symptoms start. A collaborative research team including Oak Ridge National Laboratory analyzed bacteria from a small sample of premenopausal women undergoing laparoscopic surgery for suspected endometriosis.