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An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.

UTK researchers used neutron probes at ORNL to confirm established fundamental chemical rules can also help understand and predict atomic movements and distortions in materials when disorder is introduced, as arrows show. Credit: Eric O’Quinn/UTK

Pauling’s Rules is the standard model used to describe atomic arrangements in ordered materials. Neutron scattering experiments at Oak Ridge National Laboratory confirmed this approach can also be used to describe highly disordered materials.

The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

Scientists synthesized graphene nanoribbons (yellow) on a titanium dioxide substrate (blue). The lighter ends show magnetic states. Inset: The ends have up and down spin, ideal for creating qubits. Credit: ORNL, U.S. Dept. of Energy

An international multi-institution team of scientists has synthesized graphene nanoribbons – ultrathin strips of carbon atoms – on a titanium dioxide surface using an atomically precise method that removes a barrier for custom-designed carbon

Substituting deuterium for hydrogen makes methylammonium heavier and slows its swaying so it can interact with vibrations that remove heat, keeping charge carriers hot longer. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

Led by ORNL and the University of Tennessee, Knoxville, a study of a solar-energy material with a bright future revealed a way to slow phonons, the waves that transport heat.

The n-helium-3 precision experiment, conducted at ORNL, measured the weak force between protons and neutrons by detecting the tiny electrical signal produced when a neutron and a helium-3 nucleus combine and then decay as they move through the helium gas target cell. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

Through a one-of-a-kind experiment at ORNL, nuclear physicists have precisely measured the weak interaction between protons and neutrons. The result quantifies the weak force theory as predicted by the Standard Model of Particle Physics.

Paul Abraham uses mass spectrometry to study proteins.

Systems biologist Paul Abraham uses his fascination with proteins, the molecular machines of nature, to explore new ways to engineer more productive ecosystems and hardier bioenergy crops.

Weili Xiong collaborated on the mass spectrometry research while at ORNL as a postdoctoral associate.

Scientists at Oak Ridge National Laboratory and Ohio State University discovered a new microbial pathway that produces ethylene, providing a potential avenue for biomanufacturing a common component of plastics, adhesives, coolants and other everyday products.

ORNL’s Lab-on-a-crystal uses machine learning to correlate materials’ mechanical, optical and electrical responses to dynamic environments. Credit: Ilia Ivanov/ORNL, U.S. Dept. of Energy

An all-in-one experimental platform developed at Oak Ridge National Laboratory’s Center for Nanophase Materials Sciences accelerates research on promising materials for future technologies.

four circle diffractometer

A UCLA-led team that discovered the first intrinsic ferromagnetic topological insulator – a quantum material that could revolutionize next-generation electronics – used neutrons at Oak Ridge National Laboratory to help verify their finding.