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Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

ORNL scientists are currently using Proto-MPEX to perform necessary research and development that is needed to build MPEX. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Temperatures hotter than the center of the sun. Magnetic fields hundreds of thousands of times stronger than the earth’s. Neutrons energetic enough to change the structure of a material entirely.

Omar Demerdash

With the rise of the global pandemic, Omar Demerdash, a Liane B. Russell Distinguished Staff Fellow at ORNL since 2018, has become laser-focused on potential avenues to COVID-19 therapies.

Coronavirus graphic

In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.

Kat Royston

As a teenager, Kat Royston had a lot of questions. Then an advanced-placement class in physics convinced her all the answers were out there.

Postdoctoral researcher Nischal Kafle positions a component for a portable plasma imaging diagnostic device at ORNL in February. The device, a project for ARPA-E, is built of off-the-shelf parts. Credit: Carlos Jones/ORNL

The techniques Theodore Biewer and his colleagues are using to measure whether plasma has the right conditions to create fusion have been around awhile.

Scientists created a novel polymer that is as effective as natural proteins in transporting protons through a membrane. Credit: ORNL/Jill Hemman

Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.

The image visualizes how the team’s multitask convolutional neural network classifies primary cancer sites. Image credit: Hong-Jun Yoon/ORNL

As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.

Liane Russell

A select group gathered on the morning of Dec. 20 at the Department of Energy’s Oak Ridge National Laboratory for a symposium in honor of Liane B. Russell, the renowned ORNL mammalian geneticist who died in July.