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ORNL has developed bacterial strains that can utilize a common plastic co-monomer as a feedstock. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.
Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).
Real-time tracking and monitoring of radioactive/nuclear materials during transportation is a critical need to ensure safety and security. Current technologies rely on simple tagging, using sensors attached to transport containers, but they have limitations.
Due to a genes unique nucleotide sequences acquired through horizontal gene transfer, the gene has a transcriptional repressor activity and innate enzymatic role.
We have developed bacterial strains that can convert sustainable feedstocks and waste feedstocks into chemical precursors for next generation plastics.
ORNL has identified a panel of novel nylon hydrolases with varied substrate and product selectivity.
Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.