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High and ultra-high vacuum applications require seals that do not allow leaks. O-rings can break down over time, due to aging and exposure to radiation. Metallic seals can damage sealing surfaces, making replacement of the original seal very difficult.

ORNL has developed bacterial strains that can utilize a common plastic co-monomer as a feedstock. This will help enable modern, petroleum-derived plastics to be converted into value-added chemicals.

Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).

Due to a genes unique nucleotide sequences acquired through horizontal gene transfer, the gene has a transcriptional repressor activity and innate enzymatic role.

We have developed bacterial strains that can convert sustainable feedstocks and waste feedstocks into chemical precursors for next generation plastics.

ORNL has identified a panel of novel nylon hydrolases with varied substrate and product selectivity.

Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.

There is a critical need for new antiviral drugs for treating infections of severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).

The invention provides on-line analysis of droplets for mass spectrometry.

The invention provides a gene and methods for maintaining meiotic chromosomal architecture