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Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2).

An ultrabroadband, polarization-entangled photon source for C+L-band quantum networks, enabling adaptive, high-fidelity entanglement distribution.

Due to a genes unique nucleotide sequences acquired through horizontal gene transfer, the gene has a transcriptional repressor activity and innate enzymatic role.

We have developed bacterial strains that can convert sustainable feedstocks and waste feedstocks into chemical precursors for next generation plastics.

A novel molecular sorbent system for low energy CO2 regeneration is developed by employing CO2-responsive molecules and salt in aqueous media where a precipitating CO2--salt fractal network is formed, resulting in solid-phase formation and sedimentation.

ORNL has identified a panel of novel nylon hydrolases with varied substrate and product selectivity.

Technologies directed quantum spectroscopy and imaging with Raman and surface-enhanced Raman scattering are described.

Genetic modification of microbes that are thermophiles—ones that grow at elevated temperatures—is extremely challenging. Tools developed for E. coli, a typical host for protein production, typically do not function at elevated temperatures.