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ORNL’s Adam Guss began adapting the SAGE gene editing tool to modify microbes in graduate school. Today, SAGE is rapidly accelerating the design of custom microbes for a variety of applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.

Initially, Celeritas will accelerate simulation of data from the Compact Muon Solenoid detector (shown schematically) at CERN’s Large Hadron Collider. Credit: Seth Johnson/ORNL, U.S. Dept. of Energy

Scientists at the Department of Energy’s Oak Ridge National Laboratory are leading a new project to ensure that the fastest supercomputers can keep up with big data from high energy physics research.

Technology to retrofit nonpowered dams such as the Lake Sequoyah Dam in North Carolina could be tested before deploying to ensure performance and reliability. Credit: Scott DeNeale/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory have identified a key need for future hydropower innovations – full-scale testing – to better inform developers and operators before making major investments.

ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Conduit hydropower presents opportunities in every state. Credit: ORNL, U.S. Dept. of Energy

Millions of miles of pipelines and conduits across the United States make up an intricate network of waterways used for municipal, agricultural and industrial purposes.

ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

ORNL is studying how climate change may impact water availability for hydropower facilities such as the Shasta Dam and Lake in California. Credit: U.S. Bureau of Reclamation

ORNL has provided hydropower operators with new data to better prepare for extreme weather events and shifts in seasonal energy demands caused by climate change.

ORNL’s RapidCure improves lithium-ion electrode production by producing electrodes faster, reducing the energy necessary for manufacturing and eliminating the need for a solvent recycling unit. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Researchers at the Department of Energy’s Oak Ridge National Laboratory and their technologies have received seven 2022 R&D 100 Awards, plus special recognition for a battery-related green technology product.

Bobby Sumpter. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL Corporate Fellow and Center for Nanophase Materials Sciences researcher Bobby Sumpter has been named fellow of two scientific professional societies: the Institute of Physics and the International Association of Advanced Materials.

Innovation Crossroads Cohort Six includes: Bianca Bailey, Agriwater; Rajan Kumar, Ateois Systems; Alex Stiles, Vitriform3D; Kim Tutin, Captis Aire; Anca Timofte, Holocene Climate; and Pete Willette, facil.ai. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory’s Innovation Crossroads program welcomes six new science and technology innovators from across the United States to the sixth cohort.