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Media Contacts
![Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/rs_0.jpg?h=71976bb4&itok=nFsgqwUT)
Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.
![Plutonium oxide is loaded onto a truck for shipping. Adam Parkison/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-09/PXL_20230620_120836896_0.jpg?h=2848f5af&itok=Nh31DLuy)
In June, ORNL hit a milestone not seen in more than three decades: producing a production-quality amount of plutonium-238
![An illustration shows how the composite is pressed into a seamless aluminum liner, which is then sealed with an aluminum powder cap. The research is sponsored by the DOE Isotope Program. Credit: Chris Orosco/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-06/RadiumTargetIllustration_0.png?h=cba57ff2&itok=Hhq-h9v8)
Oak Ridge National Laboratory researchers have developed a method to simplify one step of radioisotope production — and it’s faster and safer.
![Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-09/radium_0.jpg?h=dbdf53bf&itok=dMlhyVKO)
Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.
![Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.](/sites/default/files/styles/list_page_thumbnail/public/2021-08/Part%20of%20Th-228%20Team_1.jpg?h=09b6d1d3&itok=1_l1hx2l)
As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.
![Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-03/gif_high_res.gif?h=ae1281eb&itok=QtNBjm3O)
A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.
![Brian Damiano](/sites/default/files/styles/list_page_thumbnail/public/2020-12/2016-P04442.jpg?h=49ab6177&itok=lPIC-H6L)
Brian Damiano, head of the Centrifuge Engineering and Fabrication Section, has been elected fellow of the American Society of Mechanical Engineers.
![asset management](/sites/default/files/styles/list_page_thumbnail/public/2023-05/Picture9.png?h=cf4f3851&itok=rVU02eNT)
East Tennessee occupies a special place in nuclear history. In 1943, the world’s first continuously operating reactor began operating on land that would become ORNL.
![Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.](/sites/default/files/styles/list_page_thumbnail/public/2020-10/2020-P15712.jpg?h=036a71b7&itok=6cpxN4v2)
When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.
![Methanotroph_OB3b_cells Methanotroph_OB3b_cells](/sites/default/files/styles/list_page_thumbnail/public/Methanotroph_OB3b_cells_2.jpg?itok=Iml9vTIS)
A team led by the Department of Energy’s Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and sup...