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Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy

Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.

: This schematic of tokamak core-pedestal-boundary regions show what will be simulated by an ORNL project applying machine learning to plasma physics modeling. Credit: Giacomin et al., J. Comput. Phys., 463, (2022) 111294, https://doi.org/10.1016/j.jcp.2022.11294

ORNL will lead three new DOE-funded projects designed to bring fusion energy to the grid on a rapid timescale.

HFIR

Creating energy the way the sun and stars do — through nuclear fusion — is one of the grand challenges facing science and technology. What’s easy for the sun and its billions of relatives turns out to be particularly difficult on Earth.

The Fuel Pellet Fueling Laboratory at ORNL is part of a suite of fusion energy R&D capabilities and provides test equipment and related diagnostics for carrying out experiments to develop pellet injectors for plasma fueling applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL will team up with six of eight companies that are advancing designs and research and development for fusion power plants with the mission to achieve a pilot-scale demonstration of fusion within a decade.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Mars Rover 2020

More than 50 current employees and recent retirees from ORNL received Department of Energy Secretary’s Honor Awards from Secretary Jennifer Granholm in January as part of project teams spanning the national laboratory system. The annual awards recognized 21 teams and three individuals for service and contributions to DOE’s mission and to the benefit of the nation.

Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.

As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.

When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.

 Using the ASGarD mathematical framework, scientists can model and visualize the electric fields, shown as arrows, circling around magnetic fields that are colorized to represent field magnitude of a fusion plasma. Credit: David Green/ORNL

Combining expertise in physics, applied math and computing, Oak Ridge National Laboratory scientists are expanding the possibilities for simulating electromagnetic fields that underpin phenomena in materials design and telecommunications.