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![Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/Slide1_0.png?h=c855054e&itok=aNbgxXsc)
Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.
![(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.](/sites/default/files/styles/list_page_thumbnail/public/2019-03/TourassiWH%5B1%5D.png?h=26b5064d&itok=HUC2iYmE)
OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.
![Coexpression_hi-res_image[1].jpg Coexpression_hi-res_image[1].jpg](/sites/default/files/styles/list_page_thumbnail/public/Coexpression_hi-res_image%5B1%5D_0.jpg?itok=OnLe-krT)
While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.
![Nuclear—Deep space travel Nuclear—Deep space travel](/sites/default/files/styles/list_page_thumbnail/public/Screen%20Shot%202018-12-19%20at%2010.29.32%20AM.png?itok=hq0dlVIf)
By automating the production of neptunium oxide-aluminum pellets, Oak Ridge National Laboratory scientists have eliminated a key bottleneck when producing plutonium-238 used by NASA to fuel deep space exploration.
![Rose Ruther and Jagjit Nanda have been collaborating to develop a membrane for a low-cost redox flow battery for grid-scale energy storage. Rose Ruther and Jagjit Nanda have been collaborating to develop a membrane for a low-cost redox flow battery for grid-scale energy storage.](/sites/default/files/styles/list_page_thumbnail/public/MembraneRoseJagjitFilterSmile.jpg?itok=p8-Q46wn)
Oak Ridge National Laboratory scientists have developed a crucial component for a new kind of low-cost stationary battery system utilizing common materials and designed for grid-scale electricity storage. Large, economical electricity storage systems can benefit the nation’s grid ...
For the past six years, some 140 scientists from five institutions have traveled to the Arctic Circle and beyond to gather field data as part of the Department of Energy-sponsored NGEE Arctic project. This article gives insight into how scientists gather the measurements that inform t...
Scientists at Oak Ridge National Laboratory have conducted a series of breakthrough experimental and computational studies that cast doubt on a 40-year-old theory describing how polymers in plastic materials behave during processing.
![Oak Ridge National Laboratory researcher Halil Tekinalp combines silanes and polylactic acid to create supertough renewable plastic. Oak Ridge National Laboratory researcher Halil Tekinalp combines silanes and polylactic acid to create supertough renewable plastic.](/sites/default/files/styles/list_page_thumbnail/public/news/images/02%20Materials-Supertough_bioplastic.jpg?itok=64jAyN8y)
A novel method developed at Oak Ridge National Laboratory creates supertough renewable plastic with improved manufacturability. Working with polylactic acid, a biobased plastic often used in packaging, textiles, biomedical implants and 3D printing, the research team added tiny amo...
![Default image of ORNL entry sign](/sites/default/files/styles/list_page_thumbnail/public/2023-09/default-thumbnail.jpg?h=553c93cc&itok=N_Kd1DVR)
Scientists of the Next-Generation Ecosystem Experiments are blogging from the Arctic this summer. Follow their adventures at http://ngee-arctic.blogspot.com/. Participants share troubles and triumphs from the field in entries with headings like "Flying Wild Alaska" and "Hitting the Tundra." "The b...